One Pot Synthesis of tetrahydroquinoline-5-thiones and Evaluation of their Antimicrobial Activities

Abstract

One-pot syntheses of various tetrahydroquinoline-5-thiones are reported. The antimicrobial activity of the obtained products against various types of bacteria was estimated.

3-Cyano-8-methyl-2-oxo-1,4-disubstituted-1,2,5,6,7,8-hexahydroquinolines: synthesis and biological evaluation as antimicrobial and cytotoxic agents

“…In recent years, pyridines and some derived fused-ring systems such as quinolines have attracted much attention as versatile chemotherapeutic agents owing to their reported potential antimicrobial activity [4][5][6] , in addition to various antineoplastic 7 , antiproliferative 8 , and cytotoxic 9 potentials. Furthermore, particular interest has been given to cyanopyridine derivatives as anticancer and antiviral 10 agents.…”