One-pot synthesis of sulfur heterocycles from simple organic substrates

Abstract

Sulfur-nitrogen heterocycles are important compounds due to their unusual physical properties and significant and versatile biological activity. A novel strategy for their preparation from readily available organic substrates with the employment of sulfur monochloride is proposed. A synthesis of wide range of heterocyclic systems including 1,2-dithioles, 1,2,3,4,5-pentathiepins, 1,2,3-dithiazoles, 1,4-thiazines, 1,2,3,4,5,6,7-heptathiocanes and others, in a cascade transformations has been developed.

Synthesis of some new Heterocyclic Compounds and Schiff bases of 4-phenyl-3-ene-butanone and study their liquid crystal properties

“…α,β-Unsaturated ketones like Chalcons undergo a variety of useful reactions to produce a large number of their derivatives specialy heterocyclic derivatives [1][2][3][4][5]. A large number of Schiff bases were prepared and their biological activity were investigated and found to be very good antibacterial, antifungal agents [6][7][8].…”

Direct Exchange of Oxygen and Selenium Atoms in the 1,2,5-Oxadiazoles and 1,2,5-Selenadiazoles by Action of Sulfur Monochloride

“…A specific feature of sulfur monochloride (S 2 Cl 2 ) is its diverse reactivity [15,16,17,18]. The most useful property of this compound is its sulfurating ability.…”