One-pot synthesis of stable and functional hydrophilic CsPbBr<sub>3</sub> perovskite quantum dots for “turn-on” fluorescence detection of <i>Mycobacterium tuberculosis</i>

Jiang, Xue; Zeng, Hongwei; Duan, Changyuan; Hu, Qianfang; Wu, Qiaomin; Yu, Yang; Yang, Xiaolan

doi:10.1039/d1dt03624f

Cited by 12 publications

(8 citation statements)

References 56 publications

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“…When using OA and OAm surface ligands to modify CsPbBr 3 PNCs, the LARP method is simple and does not require high experimental environment. 32 Therefore, OA-OAm-CsPbBr 3 (LARP) is synthesized by LARP using OA and OAm ligands. The microstructures are characterized by TEM and HRTEM.…”

Section: Morphology and Structure Characterizationmentioning

confidence: 99%

“…Figure 1f shows the XRD characterization results of OA-OAm-CsPbBr 3 (LARP) and OA-OAm-CsPbBr 3 @SiO 2 (LARP). The diffraction peaks at 15.2°, 21.5°and 30.7°correspond to the (100), ( 110) and (200) crystal faces in the standard XRD card of CsPbBr 3 (PDF#18−0364), 34 indicating that SiO 2 coating does not change the crystal structure of OA-OAm-CsPbBr 3 (LARP). The experimental results show that OA-OAm-CsPbBr 3 (LARP) and OA-OAm-CsPbBr 3 @SiO 2 (LARP) are synthesized successfully, but the size of OA-OAm-CsPbBr 3 (LARP) is not uniform and there is a problem that OA-OAm-CsPbBr 3 @SiO 2 (LARP) contains multiple nuclei in one shell.…”

Section: Morphology and Structure Characterizationmentioning

confidence: 99%

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Highly Stable and Biocompatible CsPbBr₃ Nanocrystals Synthesized by Different Methods for Bioimaging Applications

Xue,

Chen,

Zhang

et al. 2024

ACS Appl. Nano Mater.

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The low stability and high toxicity of CsPbBr 3 perovskite nanocrystals (PNCs) greatly limit their application in the biological field. Here, six different CsPbBr 3 PNCs were prepared by ligand-assisted reprecipitation (LARP) and hot injection using oleic acid (OA), oleamine (OAm), (3-Aminopropyl) triethoxysilane (APTES) modification and SiO 2 coating, respectively. Different ligands, shells, and synthesis methods give CsPbBr 3 PNCs diverse optical properties, stability, and biocompatibility. Among them, OA-OAm-APTES-CsPbBr 3 @SiO 2 has the highest photoluminescence quantum yield (PLQY) (80.74%) and higher stability (fluorescence intensity remains 70% after 15 days in an atmospheric environment). OA-OAm-APTES-CsPbBr 3 @SiO 2 (30 μg/mL) was cocultured with liver cancer cells for 12 h, and the survival rate was 80%, indicating high biocompatibility. Under the observation of the microplate reader, bright green fluorescence appeared in the cytoplasm, indicating that OA-OAm-APTES-CsPbBr 3 @SiO 2 has great application potential in the field of bioimaging.

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Section: Morphology and Structure Characterizationmentioning

confidence: 99%

Section: Morphology and Structure Characterizationmentioning

confidence: 99%

Highly Stable and Biocompatible CsPbBr₃ Nanocrystals Synthesized by Different Methods for Bioimaging Applications

Xue,

Chen,

Zhang

et al. 2024

ACS Appl. Nano Mater.

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“…This is an inspiring work in detecting PA in water. Through a one-pot synthetic method, stable carboxyl group-functionalized CsPbBr 3 –COOH QDs were developed by using amino-poly(ethylene glycol)-carboxyl and perfluorooctyltriethoxylsilane as ligands and were engaged in the PL “turn-on” detection of Mycobacterium tuberculosis (Mtb) [ 188 ].…”

Section: Cspbx 3 (X = CL Br and I) And Composites ...mentioning

confidence: 99%

Sensing Utilities of Cesium Lead Halide Perovskites and Composites: A Comprehensive Review

Shellaiah,

Sun,

Thirumalaivasan

et al. 2024

Sensors

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Recently, the utilization of metal halide perovskites in sensing and their application in environmental studies have reached a new height. Among the different metal halide perovskites, cesium lead halide perovskites (CsPbX3; X = Cl, Br, and I) and composites have attracted great interest in sensing applications owing to their exceptional optoelectronic properties. Most CsPbX3 nanostructures and composites possess great structural stability, luminescence, and electrical properties for developing distinct optical and photonic devices. When exposed to light, heat, and water, CsPbX3 and composites can display stable sensing utilities. Many CsPbX3 and composites have been reported as probes in the detection of diverse analytes, such as metal ions, anions, important chemical species, humidity, temperature, radiation photodetection, and so forth. So far, the sensing studies of metal halide perovskites covering all metallic and organic–inorganic perovskites have already been reviewed in many studies. Nevertheless, a detailed review of the sensing utilities of CsPbX3 and composites could be helpful for researchers who are looking for innovative designs using these nanomaterials. Herein, we deliver a thorough review of the sensing utilities of CsPbX3 and composites, in the quantitation of metal ions, anions, chemicals, explosives, bioanalytes, pesticides, fungicides, cellular imaging, volatile organic compounds (VOCs), toxic gases, humidity, temperature, radiation, and photodetection. Furthermore, this review also covers the synthetic pathways, design requirements, advantages, limitations, and future directions for this material.

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“…In another study, hydrophilic CsPbBr 3 quantum dots were functionalized using carboxyl groups and used as a biosensor for DNA detection of Mtb . The study showed low LOD of this biosensing system (51.9 pM) and was also efficient in the detection of drug resistant strains [ 179 ].…”

Section: Nanomaterials For Tb Diagnosticsmentioning

confidence: 99%

Evolution of tuberculosis diagnostics: From molecular strategies to nanodiagnostics

2023

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One-pot synthesis of stable and functional hydrophilic CsPbBr₃ perovskite quantum dots for “turn-on” fluorescence detection of Mycobacterium tuberculosis

Abstract: All-inorganic CsPbBr3 perovskite quantum dots (QDs) are widely studied owing to their excellent optoelectronic properties, however they are usually hydrophobic and unstable in water that seriously limit their biomedical applications....

Cited by 12 publications

References 56 publications

Highly Stable and Biocompatible CsPbBr₃ Nanocrystals Synthesized by Different Methods for Bioimaging Applications

Highly Stable and Biocompatible CsPbBr₃ Nanocrystals Synthesized by Different Methods for Bioimaging Applications

Sensing Utilities of Cesium Lead Halide Perovskites and Composites: A Comprehensive Review

Evolution of tuberculosis diagnostics: From molecular strategies to nanodiagnostics

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One-pot synthesis of stable and functional hydrophilic CsPbBr3 perovskite quantum dots for “turn-on” fluorescence detection of Mycobacterium tuberculosis

Abstract: All-inorganic CsPbBr3 perovskite quantum dots (QDs) are widely studied owing to their excellent optoelectronic properties, however they are usually hydrophobic and unstable in water that seriously limit their biomedical applications....

Cited by 12 publications

References 56 publications

Highly Stable and Biocompatible CsPbBr3 Nanocrystals Synthesized by Different Methods for Bioimaging Applications

Highly Stable and Biocompatible CsPbBr3 Nanocrystals Synthesized by Different Methods for Bioimaging Applications

Sensing Utilities of Cesium Lead Halide Perovskites and Composites: A Comprehensive Review

Evolution of tuberculosis diagnostics: From molecular strategies to nanodiagnostics

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Product

Resources

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One-pot synthesis of stable and functional hydrophilic CsPbBr₃ perovskite quantum dots for “turn-on” fluorescence detection of Mycobacterium tuberculosis

Highly Stable and Biocompatible CsPbBr₃ Nanocrystals Synthesized by Different Methods for Bioimaging Applications

Highly Stable and Biocompatible CsPbBr₃ Nanocrystals Synthesized by Different Methods for Bioimaging Applications