One-pot synthesis of magnetic molecularly imprinted microspheres by RAFT precipitation polymerization for the fast and selective removal of 17β-estradiol

Abstract

A facile strategy was developed to prepare magnetic molecularly imprinted microspheres (MMIMs) for the selective recognition and effective removal of 17-beta-estradiol (17b-E2) by reversible additionfragmentation chain transfer precipitation polymerization. One-pot synthesis was employed, which could simplify the imprinting process and shorten the experimental period. The resultant MMIMs displayed fast kinetics and high binding capacity, and the adsorption processes followed LangmuirFreundlich isotherm and pseudo-second-order kinetic models. Excellent recognition selectivity toward 17b-E2 was attained over other phenolic estrogens such as 17-alpha-E2, estriol and estrone. The magnetic property of MMIMs provided fast and simple separation, and the recycling process for magnetic solid phase extraction (MSPE) was sustainable at least five times without obvious efficiency decrease. Furthermore, the MMIMs-MSPE presented satisfactory recoveries within 71.7-108.3% with the precisions of 1.1-6.0% for spiked 17b-E2 in water, soil and food samples. The developed MMIMs-based method proved to be a convenient and practical way in sample pretreatment and targeted pollutants removal.

Metal organic frameworks (MOFs) for magnetic solid-phase extraction of pyrazole/pyrrole pesticides in environmental water samples followed by HPLC-DAD determination

“…The magnetic nanoparticle-adsorbed target compounds can be easily collected by an external magnetic field without additional centrifugation or filtration of samples [15]. Also, metal-organic frameworks (MOFs), crystalline solids consisting of metal ions coordinated by organic ligands to form rigid three dimensional frameworks, have received increasing concerns owing to their unique properties such as high surface area, high pore volume and chemical tenability [16][17][18] mg/L of chlorfenapyr dissolved in n-hexane were purchased from National Research Center for Certified Reference Materials (Beijing, China), which were all stored at -20 ºC.…”

Synthesis of magnetic molecularly imprinted polymers by reversible addition fragmentation chain transfer strategy and its application in the Sudan dyes residue analysis

“…Thus, a sensitive and faster method for the identification and quantification of such Sudan dyes in foods is required urgently. Although MMIPs developed by RAFT methodology [12,[28][29][30][31] and the separation of Sudan dyes from chilli powder by MIPs [32][33][34] are reported, the MMIP made by RAFT technology for the extraction and separation of Sudan dyes have never been reported so far.…”

Synthesis of mimic molecularly imprinted ordered mesoporous silica adsorbent by thermally reversible semicovalent approach for pipette-tip solid-phase extraction-liquid chromatography fluorescence determination of estradiol in milk

“…Until now, there are some studies of molecularly imprinted polymers on estradiol have been reported [17][18][19]. Currently, there are three strategies, namely covalent, non-covalent and semicovalent imprinting, for preparing molecularly imprinted materials [20].…”