One-pot synthesis of indole-fused nitrogen heterocycles via the direct C(sp²)–H functionalization of naphthoquinones; accessibility for deep red emitting materials

Abstract

A convenient one-pot, two-step methodology was developed for the transformation of readily available planar naphthoquinone derivatives into structurally complex indole-fused nitrogen heterocycles under aerobic conditions.

The Relevance and Insights on 1,4-Naphthoquinones as Antimicrobial and Antitumoral Molecules: A Systematic Review

“…Recently, Kumari et al, 2022, reported the indole-fused nitrogen heterocycles by twostep methodology, directly modifying the NQ ring. This compound can be used as solidstate fluorescence material (Figure 13) [60]. The nucleophilic substitution of 2,3-dichloro-1,4-naphthoquinone is a synthetic strategy for introducing nitrogen, oxygen, carbon, sulfur, and selenium nucleophiles at C2 and C3 positions [61].…”

“…Mahalap- Recently, Kumari et al, 2022, reported the indole-fused nitrogen heterocycles by two-step methodology, directly modifying the NQ ring. This compound can be used as solid-state fluorescence material (Figure 13) [60]. Recently, Kumari et al, 2022, reported the indole-fused nitrogen heterocycles by twostep methodology, directly modifying the NQ ring.…”

Organocatalytic asymmetric cascade bicyclization: access to chiral polycyclic bisindoles from 2-indolylmethanols and propargylic alcohols

“…Chiral indole-fused heterocycles are frequently encountered in natural products, bioactive molecules, and functional materials (Scheme 1). 1 Notably, bisindole alkaloids have garnered significant attention due to their superior biological activities compared to monoindole alkaloids against various cancer cell lines. 2 In these bisindole derivatives, one of the indole units is typically present with substituents, such as widely explored bis(indolyl)methanes.…”