One-pot synthesis of fluorine containing 3-cyano/ethoxycarbonyl-2-methyl-benzo[b]furans

Five‐Membered Heterocycles: Benzofuran and Related Systems

“…3-Cyano or ethoxycarbonyl-2-methyl-benzo [b]furans have been prepared in a onestep synthesis by the microwave induced Claisen rearrangement under solvent-free conditions (Scheme 7.53) [90]. The Fries rearrangement has been employed in the synthesis of benzo [b]naphtha[2,3-d]furan-6,11-dione [91].…”

Synthesis and Antimicrobial Activity of N‐Aryl‐4‐(cyano/alkoxycarbonyl)‐5‐(pyridin‐3‐yl)‐1H/3H‐1,2,3‐triazole Derivatives

“…The synthesis of N ‐aryl‐5‐(pyridinyl)‐1 H /3 H ‐1,2,3‐triazole‐4‐carbonitriles is not reported so far. As part of our investigations on the conjugated alkynes , we have recently reported the synthesis of a new series of pyridine‐3‐yl‐substituted propynenitriles and acetylenic carboxylic acid esters by the intra‐molecular Wittig reaction of β‐oxo‐alkylidenetriphenylphosphoranes using microwave irradiation and conventional heating . The chloronicotinyl substituted acetylenic compounds have exhibited good antimicrobial activity.…”

Microwave-assisted Synthesis of 6-{(5-Aryl-1,3,4-oxadiazol-2-yl)methyl}-6H-indolo[2,3-b]quinoxalines

“…Several synthetic methods employing microwave irradiation under both homogeneous and heterogeneous reaction conditions were practiced in preparing different heterocyclic compounds . As part of our research on the preparation of new heterocyclic compounds using green reaction conditions, we have developed microwave‐assisted synthetic protocols for building various heterocyclic scaffolds . Recently, we have prepared novel 6‐( N ‐aryl‐1 H ‐1,2,3‐triazol‐4‐yl‐methyl)‐6 H ‐indolo[3,2‐ b ]quinoxaline derivatives with moderate cytotoxicity against different human cancer cell lines .…”