One-Pot Synthesis of Benzoxazines Through Mannich Condensations

Abstract

Five benzoxazine were synthesized by Mannich condensation reaction between 2,4-ditert-butyl phenol, formaldehyde and different amines in one pot synthesis. The benzoxazines were characterized by elemental analysis, spectral and crystal structure determination. The synthesis process requires considerable less time and three of the five benzoxazines are new and reported for the first time.