One‐pot Synthesis of 4‐Aryl‐NH‐1,2,3‐triazoles in Presence of Fe₃O₄@SiO₂@Propyl‐HMTA as a New Basic Catalyst

Abstract

In this paper, hexamethylenetetramine-functionalized magnetic Fe 3 O 4 nanoparticles (Fe 3 O 4 @SiO 2 @Propyl-HMTA) catalyst was prepared and utilized for the synthesis of 4-aryl-NH-1,2,3triazole derivatives. Also, the interaction between aldehyde, nitromethane, and sodium azide was investigated within the synthesis route. Henry Reaction between the aldehyde and nitromethane created an intermediate that was immediately attacked by N 3 À . As a result of this attack, 4-aryl-NH-1,2,3triazole was generated through an in situ [3 + 2] cycloaddition.

Decarboxylative Cross‐coupling Reaction between Aryl Carboxylic Acids using BF@Propyl/Tris/Pd as a Novel Catalyst

“…Herein, regarding the stabilization of palladium on the novel support, [28][29][30] now, we focus on further improve of the catalytic efficiency. Therefore, we present decarboxylative cross-coupling reactions using this promising procedure.…”

Detection of tetanus toxoid with iron magnetic nanobioprobe

“…Spectrum A in figure 2 belongs to iron oxide nanoparticle, which absorption bands in the 559 and 632 cm −1 region correspond to the stretching vibration of Fe-O bonds and the absorption band in the 3416 cm −1 region corresponds to the stretching and bending vibrations of hydroxyl groups (-OH) in the crystal network of nanoparticles [48][49][50][51][52][53][54]. B spectrum by adding TEOS to iron oxide nanoparticles, the absorption band is observed in the range between 948 and 1078 cm −1 and 796 cm −1 .…”

Boronic acid functionalized silica‐coated Fe3O4 as a novel magnetically separable catalyst for the synthesis of hydrazinyl thiazoles

“…The increase in catalyst quantity to 15 mg produced no significant improvement in the model reaction (Table 1, entry 12). The catalytic efficacy of Fe 3 O 4 , Fe 3 O 4 @SiO 2, and B (OH) 3 was also tested for the model reaction and found to produce a lower yield of 4a as compared to the synthesized catalyst (Table 1, entries [13][14][15].…”

“…11,12 Nano-sized Fe 3 O 4 is the most important magnetic support as well as a heterogeneous catalyst that has received considerable attention owing to its insolubility in the reaction medium, and high magnetization value which allows easy magnetic separation from the reaction medium. 13,14 Moreover, the Fe 3 O 4 magnetic nanoparticles (MNPs) find enormous applications in the field of biomolecular sensors, hyperthermia, drug delivery, magnetic resonance imaging (MRI), etc. [15][16][17][18][19] On the other hand, Fe 3 O 4 MNPs have limitations of rapid aggregation into large clusters and chemical instability in the drastic reaction environment.…”

“…The nano size of the ferrites enhances their catalytic activity due to their large surface area 11,12 . Nano‐sized Fe 3 O 4 is the most important magnetic support as well as a heterogeneous catalyst that has received considerable attention owing to its insolubility in the reaction medium, and high magnetization value which allows easy magnetic separation from the reaction medium 13,14 . Moreover, the Fe 3 O 4 magnetic nanoparticles (MNPs) find enormous applications in the field of biomolecular sensors, hyperthermia, drug delivery, magnetic resonance imaging (MRI), etc 15–19 .…”