“…24 Previous methods utilised various catalyst such as nano-[Fe 3 O 4 @SiO 2 @R-NHMe 2 ][H 2 PO 4 ], 25 graphene oxide, 26 MIL-100(Cr)/NHEtN(CH 2 PO 3 H 2 ) 2 , 27 choline chloride/ oxalic acid, 28 IR-MOF-3-ILOAc-Fe(acac) 3 , 29 N,N-diethyl-N-sulfoethanaminium chloride 30 and nano-[Fe 3 O 4 @SiO 2 /N-propyl-1-(thiophen-2-yl)ethanimine][ZnCl 2 ] 31 to synthesised 2,4dimethoxy-THPQs. Catalyst-free synthesis of THPQs were also reported using absolute ethanol, 32 acetic acid, [33][34][35] and electrolysis in presence of alcohol. 36 In continuation of our work in multicomponent synthesis, [37][38][39][40][41][42] here, we reported the simple acetic acid-mediated multicomponent synthesis of novel PQs.…”