One-Pot Preparation of Hydrophilic Glucose Functionalized Quantum Dots for Diabetic Serum Glycopeptidome Analysis

Xie, Zehu; Feng, Quanshou; Fang, Xiang; Dai, Xinhua; Yan, Yinghua; Ding, Chuan‐Fan

doi:10.1016/j.microc.2022.107397

Cited by 4 publications

(1 citation statement)

References 32 publications

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“…play critical regulatory roles in cell cycle, growth, apoptosis, and signal transduction [1][2][3]. In addition, the occurrence and development of various diseases, including blood diseases, genetic diseases, lung diseases, neurodegenerative diseases, and cancer, are tightly related to the abnormal phosphorylation and glycosylation of proteins [4][5][6]. As the main components of proteins, peptides are biologically active substances that participate in various cellular functions in living organisms.…”

Section: Introductionmentioning

confidence: 99%

Advances in proteomics sample preparation and enrichment for phosphorylation and glycosylation analysis

et al. 2022

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As the common and significant chemical modifications, post‐translational modifications (PTMs) play a key role in the functional proteome. Affected by the signal interference, low concentration, and insufficient ionization efficiency of impurities, the direct detection of PTMs by mass spectrometry (MS) still faces many challenges. Therefore, sample preparation and enrichment are an indispensable link before MS analysis of PTMs in proteomics. The rapid development of functionalized materials with diverse morphologies and compositions provides an avenue for sample preparation and enrichment for PTMs analysis. In this review, we summarize recent advances in the application of novel functionalized materials in sample preparation for phosphoproteomes and glycoproteomes analysis. In addition, this review specifically discusses the design and preparation of functionalized materials based on different enrichment mechanisms, and proposes research directions and potential challenges for proteomic PTMs research.

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Section: Introductionmentioning

confidence: 99%

Advances in proteomics sample preparation and enrichment for phosphorylation and glycosylation analysis

et al. 2022

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Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2021–2022

Harvey

2024

Mass Spectrometry Reviews

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The use of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this review is the 12th update of the original article published in 1999 and brings coverage of the literature to the end of 2022. As with previous review, this review also includes a few papers that describe methods appropriate to analysis by MALDI, such as sample preparation, even though the ionization method is not MALDI. The review follows the same format as previous reviews. It is divided into three sections: (1) general aspects such as theory of the MALDI process, matrices, derivatization, MALDI imaging, fragmentation, quantification and the use of computer software for structural identification. (2) Applications to various structural types such as oligo‐ and polysaccharides, glycoproteins, glycolipids, glycosides and biopharmaceuticals, and (3) other general areas such as medicine, industrial processes, natural products and glycan synthesis where MALDI is extensively used. Much of the material relating to applications is presented in tabular form. MALDI is still an ideal technique for carbohydrate analysis, particularly in its ability to produce single ions from each analyte and advancements in the technique and range of applications show little sign of diminishing.

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Post-synthesis of covalent organic frameworks with dual-hydrophilic groups for specific capture of serum exosomes

Hua

Feng²,

Xie³

et al. 2022

Journal of Chromatography A

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One-Pot Preparation of Hydrophilic Glucose Functionalized Quantum Dots for Diabetic Serum Glycopeptidome Analysis

Cited by 4 publications

References 32 publications

Advances in proteomics sample preparation and enrichment for phosphorylation and glycosylation analysis

Advances in proteomics sample preparation and enrichment for phosphorylation and glycosylation analysis

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2021–2022

Post-synthesis of covalent organic frameworks with dual-hydrophilic groups for specific capture of serum exosomes

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