One-Pot Dual C–C Bond-Forming Cascade Process via Suzuki Coupling and Intramolecular Cyclocondensation: An Access to Functionalized Naphthalenes
Pradip S. Waghmare,
Sreenivasulu Chinnabattigalla,
Satyanarayana Gedu
Abstract:Naphthyl ketones encompass a class of essential compounds
of biological
and industrial significance. The development of synthetic strategies
to achieve naphthyl ketones in single-step reactions from readily
available materials is highly desirable. Herein, domino one-pot synthesis
of functionalized naphthyl ketones via intermolecular Suzuki–Miyaura
coupling, followed by intramolecular distal aldol-type condensation
with the γ-methyl/methylene groups is reported. The present
strategy displayed a comprehensive su… Show more
2-Formylarylboronic acids are used in the synthesis of carbo- and hetero-cyclic, as well as acyclic compounds under transition metal catalysis. Metal-catalyzed coupling reactions/annulations of 2-formylarylboronic acids are described in this review.
2-Formylarylboronic acids are used in the synthesis of carbo- and hetero-cyclic, as well as acyclic compounds under transition metal catalysis. Metal-catalyzed coupling reactions/annulations of 2-formylarylboronic acids are described in this review.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.