Abstract:Objective: Quercetin, a wonder flavanoid despite numerous pharmacological actions, has limited clinical applications due to solubility and permeability issues and additionally having shorter biological half-life. The goal of the current work was to design Quercetin lipid-based spherical crystals, to improve its oral bioavailability and sustain its in vivo plasma levels.
Methods: An anti-solvent precipitation method was employed to prepare quercetin spherical agglomerates using ethanol and distilled water as g… Show more
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