One pot cascade synthesis of substituted 1,2,4-triazol-3-ones

Abstract

Substituted triazolinones were prepared by a three-component reaction of aldehydes, hydrazines and azodicarboxylates using TFA as a catalyst. The procedure was convenient and efficient, utilizing readily available substrates. A plausible mechanism for the cascade process is proposed. triazolinones, cascade reactions, multicomponent reactions (MCRs), azodicarboxylates Citation:Su Y H, Jiang Z, Hong D, et al. One pot cascade synthesis of substituted 1,2,4-triazol-3-ones.