“… − This unit has also been applied as a starting material to access complex polycyclic heterocycles. − In addition, the related compounds have displayed exciting applications in optoelectronic and material science in recent years. − Due to the high synthetic and biological importance of C2-quaternary indoline-3-ones, several methods have been developed . More firmly, these methods can be broadly divided into two main categories: (i) chemoselective nucleophilic addition to preformed 2-arylindole-3-one, an activated cyclic C-acylimine (path 1, Scheme a), − and (ii) direct oxidative dearomative transformations on 2-arylindoles with various nucleophiles (path 2, Scheme a). − Additional methods − that mainly involve transition metal-catalyzed transformations − and photooxidative rearrangements − have also been developed to access this unit. Despite these existing methods, creating a more general strategy for accessing 2,2-disubstituted indolin-3-ones from 2-substituted indoles under mild conditions is highly attractive.…”