A q-deformation of the ADHMN caloron construction is considered, under which the anti-selfdual (ASD) conditions of the gauge fields are preserved. It is shown that the q-dependent Nahm data with certain constraints are crucial to determine the ASD gauge fields, as in the case of ordinary caloron construction. As an application of the q-deformed ADHMN construction, we give a q-deformed caloron of HarringtonShepard type. Some limits of the parameters are also considered.