2000
DOI: 10.1053/jvet.2000.7545
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One‐Lung Versus Two‐Lung Ventilation in the Closed‐Chest Anesthetized Dog: A Comparison of Cardiopulmonary Parameters

Abstract: OLV is a feasible procedure in anesthetized dogs to better facilitate thoracic procedures such as bronchopleural fistula repair and thoracoscopy.

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Cited by 50 publications
(54 citation statements)
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“…Both R‐ and L‐OLV caused a significant decrease in PaO 2 and SpO 2 , presumably associated with significant venous admixture when deoxygenated blood from unventilated lung regions is mixed with oxygenated blood from the ventilated side. Similar observations have been documented in several canine studies . Interestingly, PaO 2 was lower at 5 minutes after the start of OLV compared with 30 minutes, possibly because of temporal development of hypoxic pulmonary vasoconstriction (HPV), an effect that will generally mitigate the initial drop in PaO 2 .…”
Section: Discussionsupporting
confidence: 85%
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“…Both R‐ and L‐OLV caused a significant decrease in PaO 2 and SpO 2 , presumably associated with significant venous admixture when deoxygenated blood from unventilated lung regions is mixed with oxygenated blood from the ventilated side. Similar observations have been documented in several canine studies . Interestingly, PaO 2 was lower at 5 minutes after the start of OLV compared with 30 minutes, possibly because of temporal development of hypoxic pulmonary vasoconstriction (HPV), an effect that will generally mitigate the initial drop in PaO 2 .…”
Section: Discussionsupporting
confidence: 85%
“…Interestingly, PaO 2 was lower at 5 minutes after the start of OLV compared with 30 minutes, possibly because of temporal development of hypoxic pulmonary vasoconstriction (HPV), an effect that will generally mitigate the initial drop in PaO 2 . A similar response has been seen in canine models of OLV . However, the most important measure of respiratory function during anesthesia is oxygen delivery (trueD˙O 2 ) to tissues, which is a function of both CaO 2 and CI.…”
Section: Discussionsupporting
confidence: 68%
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“…During OLV selective ventilation of one lung is applied for which specific intubation, including double‐lumen tubes, endobronchial intubation, or bronchial blockers, is necessary. Positioning is technically difficult in dogs and sheep (Muneyuki et al., 1983; Fujita et al., 1993; Cantwell et al., 2000). Due to malpositioning (up to 30%) in men routine bronchoscopy after double‐lumen tube or bronchial blocker placement is certainly recommended.…”
Section: Discussionmentioning
confidence: 99%
“…The principle cardiopulmonary effects of single‐lung ventilation in human beings and dogs are decreased PaO 2 and increased shunt fraction (Lübbe et al. 1991; Shimizu et al 1997; Cantwell et al. 2000).…”
Section: Discussionmentioning
confidence: 99%