“…Single cells succeed in traversing the endothelial barrier and integrate into the parenchyma. After re-establishing intercellular contacts with neighbouring Liver Disease Outcome References α1-antitrypsin (A1AT) No clinical benefit likely due to the presence of fibrosis (Strom et al, 1997a;Strom et al, 1999) Acute liver failure Reversal of disease (Fisher et al, 2000;Soriano, 2002;Fisher & Strom, 2006;Ott et al, 2006) Argininosuccinate lyase deficiency Complete correction (Stephenne et al, 2006) Biliary atresia Partial correction -slow and continuous decrease in bilirubin levels (Khan et al, 2008) Chronic liver failure Bridge to OLT (Bilir et al 200;Strom et al 1997b;Fisher & Strom, 2006;Strom et al, 1999) Citrullinemia Partial correction -decreased citrulline and circulating ammonia at 6 months post-cell infusion (Meyburg et al, 2009a) Crigler-Najjar type 1 Partial correction -slow and continuous decrease in bilirubin levels; evidence of long term correction by hepatocyte graft (one patient was followed for > 1.5 years) (Fox et al, 1998;Ambrosino et al, 2005) Familial cholesterolemia…”