One-dimensional defective photonic crystals for the sensing and detection of protein

Elsayed, Hussein A.; El-Sayed, Hesham; Sayed, Marwa I.

doi:10.1364/ao.58.008309

Cited by 57 publications

(26 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Additionally, the RI of blood can also be calculated by considering appropriate composition of haemoglobin (RBC) and plasma. The same is represented by Equation (11).…”

Section: Bio-chemical (Hb) Sensing Analysismentioning

confidence: 99%

“…n blood = n hb × f hb + n 0 × f 0 (11) where f hb and f 0 are the volume fraction of haemoglobin and solvent respectively. Thereby, considering appropriate filling factors f hb and f 0 , its concentration can also be estimated directly from the blood sample.…”

Section: Bio-chemical (Hb) Sensing Analysismentioning

confidence: 99%

“…This improves the light-matter interaction, hence very good sensitivity at very small scale. The mentioned properties are widely explored and a number of PhC devices are proposed for various sensing applications [10][11][12][13][14][15][16][17].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Design Analysis of One-Dimensional Photonic Crystal Based Structure for Hemoglobin Concentration Measurement

Goyal¹

2020

PIER M

View full text Add to dashboard Cite

In this manuscript, a porous one-dimensional Photonic Crystal (1D-PhC) based sensor is designed for biochemical sensing application (i.e., hemoglobin concentration). The alternate layers of silicon are considered for design optimization, where the porosity is introduced to obtain the desired index contrast value. The sensing capability of the proposed design is enhanced by modifying the dispersion property of the structure. For this, a defect middle layer is deliberately introduced. The number of layers, defect layer optical thickness, and porosity values are optimized to confine a defect mode of desired wavelength. Finally, the detailed analysis of proposed structure is carried out. This provides the average sensitivity of around 323 nm/RIU (0.05 nm/(g/L) along with considerably higher Figure-of-merit (FOM) of 517 RIU −1 .

show abstract

“…Additionally, the RI of blood can also be calculated by considering appropriate composition of haemoglobin (RBC) and plasma. The same is represented by Equation (11).…”

Section: Bio-chemical (Hb) Sensing Analysismentioning

confidence: 99%

Section: Bio-chemical (Hb) Sensing Analysismentioning

confidence: 99%

See 1 more Smart Citation

Design Analysis of One-Dimensional Photonic Crystal Based Structure for Hemoglobin Concentration Measurement

Goyal¹

2020

PIER M

View full text Add to dashboard Cite

show abstract

“…Photonic crystals (PhCs) are structures made of materials with differing dielectric constants in periodic arrangements [54]. PhCs can be designed to exhibit photonic band gaps with band edge and defect modes, whose spectral positions are sensitive to environmental stimulus, such as the 1-dimension PhC structure shown in Figure 2e, in which the middle defect layer acts as an optical microcavity [51,55]. PhC structures with resonant features can be constructed in 1, 2, and 3-dimensional systems and are an emerging player in developing low-cost point-of-care (POC) biosensors [51].…”

Section: Affinity-type Biosensors With Optical Signal Amplificationmentioning

confidence: 99%

“…Defects in photonic crystals can also form resonators, such as the illustrated 1-dimensional photonic crystal structure with a defect layer in the middle. The defect layer creates a resonance in the reflectance spectrum of the structure, which can track with target concentration[55]. Here, the transmittance spectrum is shown for the microring cavity, while the transmittance of the photonic crystal would depend upon the number of resonant modes supported in the defect layer.…”

mentioning

confidence: 94%

Roadmap on Universal Photonic Biosensors for Real-Time Detection of Emerging Pathogens

et al. 2021

View full text Add to dashboard Cite

The COVID-19 pandemic has made it abundantly clear that the state-of-the-art biosensors may not be adequate for providing a tool for rapid mass testing and population screening in response to newly emerging pathogens. The main limitations of the conventional techniques are their dependency on virus-specific receptors and reagents that need to be custom-developed for each recently-emerged pathogen, the time required for this development as well as for sample preparation and detection, the need for biological amplification, which can increase false positive outcomes, and the cost and size of the necessary equipment. Thus, new platform technologies that can be readily modified as soon as new pathogens are detected, sequenced, and characterized are needed to enable rapid deployment and mass distribution of biosensors. This need can be addressed by the development of adaptive, multiplexed, and affordable sensing technologies that can avoid the conventional biological amplification step, make use of the optical and/or electrical signal amplification, and shorten both the preliminary development and the point-of-care testing time frames. We provide a comparative review of the existing and emergent photonic biosensing techniques by matching them to the above criteria and capabilities of preventing the spread of the next global pandemic.

show abstract

Interfacial Engineering Approach to Pattern Resilient Polymer Photonic Crystals with Temperature‐Responsive Optical Properties

Robertson

Obando

Qiang

2022

Adv Materials Inter

View full text Add to dashboard Cite

structures, which are stacks of alternating layers of high and low refractive index domains. At the interfaces of these domains, a portion of incident light can be reflected. The amount of reflecting light at each interface is dependent upon the contrast between the refractive index of the distinct layers, while the wavelengths that are in-phase upon reflection are determined by the product of refractive index and thickness of each layer.In general, assembly of 1D-PCs can be accomplished through bottom-up and top-down approaches, where the latter involves subsequent depositions of alternating layers, providing the ability to precisely control the reflecting wavelengths without sophisticated syntheses that are typically required in bottomup methods. [11][12][13] Many model systems have been demonstrated for constructing 1D-PCs through layer-by-layer casting, with an essential requirement that selected polymers need to have orthogonal solubilities or be crosslinkable for preventing possible film loss from dissolution. [14][15][16][17][18] However, further implementing these systems into practical applications would demand additional functionalities, preferably incorporated either through intrinsic material properties and/or simple processing methods. For example, producing patterns on 1D PC films is needed for display-relevant applications. [19,20] Previous approaches for achieving this goal often involve a combination of different synthesis and processing steps including functionalization with reactive units, [21] photolithography, [22] and crosslinking processes. [23] In these cases, portions of 1D-PCs can be removed, leaving patterns on the substrate where structural color can be present. A recent study introduced a method of generating patterns in polymer photonic crystal films through light induced, in-film polymerization of a block copolymer (BCP) to selectively swell domain sizes in desired regions of the film. [20,24] While this technology can be broadly applied to different BCP systems, it involves a batch process (closed chamber system) and requires inert atmospheres for radical polymerization, potentially hindering their scalability. Therefore, development of simple and effective methods for patterning 1D-PCs is highly desired for broadening the applications of 1D polymer PCs at large scales. Planar, 1D photonic crystals (1D-PCs) are stacks of alternating layers with different refractive indices, which can reflect specific wavelengths of light through the formation of a photonic bandgap. Typical systems for 1D-PC fabrication possess relatively limited thermal and/or chemical stabilities and may require several steps for producing patterned features. Additionally, enabling stimuli-responsive behaviors in 1D-PCs are often achieved through relatively complex chemistries that might be difficult to scale-up due to associated cost and energy consumption, presenting challenges toward their implementation in practical systems. Herein, through sequential depositions of phenolic resin (resol) and poly(vinylidene f...

show abstract

One-dimensional defective photonic crystals for the sensing and detection of protein

Cited by 57 publications

References 34 publications

Design Analysis of One-Dimensional Photonic Crystal Based Structure for Hemoglobin Concentration Measurement

Design Analysis of One-Dimensional Photonic Crystal Based Structure for Hemoglobin Concentration Measurement

Roadmap on Universal Photonic Biosensors for Real-Time Detection of Emerging Pathogens

Interfacial Engineering Approach to Pattern Resilient Polymer Photonic Crystals with Temperature‐Responsive Optical Properties

Contact Info

Product

Resources

About