“…In particular, the gradient-enhanced version of the HSQC-TOCSY experiment allows (i) a careful analysis and straightforward interpretation from clean spectra, (ii) can take profit of the sensitivity-enhanced features traditionally associated to the regular HSQC pulse scheme, and (iii) offers excellent dispersion/resolution properties associated to the much better resolved F1 X dimension [2]. In addition to the classical structure elucidation strategy based on 1 H and X chemical shift assignments, typically applied for 13 C and 15 N in molecules such as carbohydrates and peptides, the regular HSQC-TOCSY pulse scheme has also been largely modified in many different ways with the aim to measure heteronuclear long-range coupling constants, n J (XH) n > 1, in both natural abundance and labelled molecules [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21].…”