Ondansetron and Dolasetron Provide Equivalent Postoperative Vomiting Control After Ambulatory Tonsillectomy in Dexamethasone-Pretreated Children

Sukhani, Radha; Pappas, Ana Lucia; Lurie, Jordan; Hotaling, Andrew J.; Park, Albert; Fluder, Elaine

doi:10.1097/00000539-200211000-00021

Cited by 45 publications

(12 citation statements)

References 12 publications

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“…In a comparative study, dolasetron 0.5 mg kg -1 (maximum 25 mg) was as effective as ondansetron 0.15 mg kg -1 (maximum 4 mg) for the prevention of POV in children who had received dexamethasone 1 mg kg -1 (maximum 25 mg). Both antiserotonins, administered IV before the initiation of tonsillectomy, were more effective than placebo [51].…”

Section: Serotonin Receptor Antagonistsmentioning

confidence: 87%

Current Management of Vomiting After Tonsillectomy in Children

Fujii

2009

CDS

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Formal retraction notice of article entitled Current Management of Vomiting after Tonsillectomy in Children (Curr Drug Saf. 2009 Jan;4(1):62-73) by Dr Y. Fujii. This article is being retracted as a result of: Failure of Dr. Fijii's institution as well as of himself to rationalize the legitimacy of the study and/or its data as stipulated in request by the Editors-in-Chief of the journals extended on April 9, 2012.

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Section: Serotonin Receptor Antagonistsmentioning

confidence: 87%

Current Management of Vomiting After Tonsillectomy in Children

Fujii

2009

CDS

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“…One trial comparing granisetron and ondansetron and another comparing granisetron, tropisetron and ondansetron in children undergoing chemotherapy found no significant differences in efficacy outcomes 83,84. Three trials have compared dolasetron and ondansetron in children undergoing surgical procedures and these also showed no significant difference in terms of efficacy 85–87. There has been no controlled trial directly comparing ramosetron and ondansetron.…”

Section: Antiemetic Medicationsmentioning

confidence: 99%

Acute gastroenteritis: from guidelines to real life

Chow

Leung²,

Hon³

2010

CEG

108

100

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Acute gastroenteritis is a very common disease. It causes significant mortality in developing countries and significant economic burden to developed countries. Viruses are responsible for approximately 70% of episodes of acute gastroenteritis in children and rotavirus is one of the best studied of these viruses. Oral rehydration therapy is as effective as intravenous therapy in treating mild to moderate dehydration in acute gastroenteritis and is strongly recommended as the first line therapy. However, the oral rehydration solution is described as an underused simple solution. Vomiting is one of the main reasons to explain the underuse of oral rehydration therapy. Antiemetics are not routinely recommended in treating acute gastroenteritis, though they are still commonly prescribed. Ondansetron is one of the best studied antiemetics and its role in enhancing the compliance of oral rehydration therapy and decreasing the rate of hospitalization has been proved recently. The guidelines regarding the recommendation on antiemetics have been changed according to the evidence of these recent studies.

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“…Los medicamentos específicos son: dolasetrón (reduce el vómito) [23][24][25][26][27] , granisetrón (reduce el vómito) 28-32 y ondansetrón (reduce el vómito y rescates antieméticos) [28][29][30][33][34][35][36][37][38][39][40][41][42][43][44][45] .…”

Section: Antieméticos 5ht3unclassified