Oncology in Nepal

Piya, Madan Kumar; Acharya, Sandhya Chapagain

doi:10.4103/2278-330x.96490

Cited by 39 publications

(36 citation statements)

References 1 publication

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“…The biggest challenges in these countries are little community awareness of breast cancer, inadequate pathology facilities, and fragmented care systems with respect to radiotherapy and systemic treatment [68]. In Nepal, for example, there is only 1 national cancer hospital in addition to 5 specialized cancer hospitals, for a population of ∼30 million people [69]. Half of all breast cancer patients present at late stages, with only 1% in situ cancers, 7% stage I, 41% stage II, 40% stage III, and 10% stage IV [70].…”

Section: Breast Cancer Treatmentmentioning

confidence: 99%

“…Half of all breast cancer patients present at late stages, with only 1% in situ cancers, 7% stage I, 41% stage II, 40% stage III, and 10% stage IV [70]. Only 4 hospitals in the country have radiation equipment, which is available at very high cost to patients, and novel diagnostic procedures and targeted therapies are unavailable [69]. …”

Section: Breast Cancer Treatmentmentioning

confidence: 99%

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Current Status and Future Projections of Breast Cancer in Asia

2015

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Asia is the world's largest continent comprising about 3/5 of the human population. Breast cancer is the most common type of cancer and the second leading cause of cancer-related deaths among women in Asia, accounting for 39% of all breast cancers diagnosed worldwide. The incidence of breast cancer in Asia varies widely across the continent and is still lower than in Western countries, but the proportional contribution of Asia to the global breast cancer rates is increasing rapidly in parallel to the socioeconomic development. However, the mortality-to-incidence ratios are much higher for Asia than for Western countries. Most Asian countries are low- and middle-income countries (LMICs) where breast cancer presents at a younger age and a later stage, and where patients are more likely to die from the disease than those in Western countries. Moreover, diagnostic workup, treatment and palliative services are inadequate in most Asian LMICs. In this review, we present an overview of the breast cancer risk factors and epidemiology, control measures, and cancer care among Asian countries.

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Section: Breast Cancer Treatmentmentioning

confidence: 99%

Section: Breast Cancer Treatmentmentioning

confidence: 99%

Current Status and Future Projections of Breast Cancer in Asia

2015

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“…The predicted rise in female cases to male cases by 2020 could as well be true [14]. Also, the most common condition was carcinoma of the lung which has been reported as commonest cancer in Nepal [15].…”

Section: Discussionmentioning

confidence: 99%

Does Morphine Influence Blood Count in Palliative Patients? : A Longitudinal Study from an Oncology Center in Nepal

Karki¹,

Timilsina²,

Sharma³

2018

Pain Manage Med

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Introduction: Morphine has been the cornerstone of pain management in palliative care patients. The easy accessibility and availability of opioids at most tertiary care centers of Nepal have made possible, the once thought impossible fundamental right of palliative patients. The availability of morphine has not only eased the pain of palliative patients but health care providers equally. The mainstay of pain management has had its success but several subjective complaints of dry mouth, sedation, feeling of incomplete wellbeing and decreased immune function is often heard of. The present study aims at evaluating the effects of morphine on complete blood count profile in palliative care patients. Methods:Complete blood count of 114 palliative patients was estimated using an automatic hematology analyzer after 24-48 hours and 14 days of morphine administration. The data was recorded using a preformed proforma and analyzed using SPSS (20). Results:A statistically significant increase in total white blood cell count, neutrophil and platelet count was observed following morphine administration but there was a decrease in lymphocyte count (p<0.05). Also, neutrophil-lymphocyte ratio, a predictor of inflammation was found to increase (p<0.05). A non-significant increase was seen with the platelet-lymphocyte ratio (p>0.05). Conclusion:Morphine is found to influence the total white blood cells, neutrophils, and lymphocytes and NLR in palliative patients. However, withholding morphine in palliative patients is never an option. Furthermore, larger randomized controlled trials are necessary to analyze the predictive value of NLR and PLR in palliative patients.

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“…[1][2][3][4][5] In Nepal, apart from some hospital based studies which reports it to be the second most common cancer in women, pooled data shows it to be the most common cancer in females and second most common cancer in both sex. 1,[6][7][8][9] Invasive squamous carcinoma of the cervix can result from the progression of preinvasive precursor lesions called cervical intraepithelial neoplasia (CIN), or dysplasia. The rate at which invasive cancer develops from CIN is usually slow, measured in years and perhaps decades.…”

Section: Introductionmentioning

confidence: 99%

Abnormal Pap Smear Results in Outpatient Attendees in a Tertiary Care Center in Kathmandu, Nepal

Khatri

Budhathoki

Pande

et al. 2017

Med. J. Shree Birendra Hosp.

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Introduction: Cervical cancer is one of the most common cancers in the world. It is the most common cancer among females in Nepal. Progression of pre-invasive precursor lesions called Cervical Intraepithelial Neoplasia (CIN) can result in invasive cancer over years and decades. Papanicolaou smear can detect these lesions early. The aim of this paper is to study the prevalence of abnormal Pap smear test and report the results.Methods: Observational study of Pap smear of 1100 women of age 21 to 65 years attending Gynaecological outpatient department of our hospital over a period of one year. Results:Pap smear results were recorded as per Bethesda system. 35% of smears had epithelial cell abnormality with 62.82% normal smear and 2.13%infections, bacterial vaginosis (1.94%) being most common. The highest epithelial cell abnormality was Low grade squamous intraepithelial lesions (29.90%) followed by Atypical squamous cell of undetermined significance (3.2%). High grade squamous intraepithelial lesions and carcinoma were next to follow (0.97% each). 80% of cancers were Squamous cell carcinoma. Conclusion:Premalignant and malignant lesions were found to be common in cervix. Pap test is simple, quick and effective way of screening them. Screening should be done at least once for all woman after the age of 30 as benefit is maximum in this age group.

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Oncology in Nepal

Cited by 39 publications

References 1 publication

Current Status and Future Projections of Breast Cancer in Asia

Current Status and Future Projections of Breast Cancer in Asia

Does Morphine Influence Blood Count in Palliative Patients? : A Longitudinal Study from an Oncology Center in Nepal

Abnormal Pap Smear Results in Outpatient Attendees in a Tertiary Care Center in Kathmandu, Nepal

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