“…This shortage of DTIC is not the first shortage of oncolytic drugs, and it certainly will not be the last, 10 so studies must be conducted by regulatory bodies, oncology societies (American Society of Hematology and ASCO), and advocacy groups (Lymphoma Research Foundation and Leukemia and Lymphoma Society) in the United States and around the world to look into underlying causes. There are many contributing factors that affect the supply of oncolytic drugs, chemotherapeutics, and biologics alike.…”