Oncological and Functional Outcomes of Primary and Salvage Total Laryngectomy

Bertolin, Andy; Lionello, Marco; Zanotti, Claudia; Franz, Leonardo; Giacomelli, Luciano; Rizzotto, Giuseppe

doi:10.1002/lary.28955

Cited by 9 publications

(12 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Le pharyngostome est la complication post-opératoire la plus fréquente après une laryngectomie totale [5,10,11]. Son incidence varie entre 3 et 65% [12][13][14]. Dans notre série, elle était de 13,5%.…”

Section: Discussionunclassified

“…Dans notre série, elle était de 13,5%. L'hématome et l'infection post-opératoire sont rares [14]. L'ablation du larynx s'accompagne de troubles fonctionnels importants pouvant altérer considérablement la qualité de vie du patient [15,16].…”

Section: Discussionunclassified

“…Elles compliquent le plus souvent les laryngectomies partielles [18,19]. La dysphagie post-laryngectomie totale est relativement rare aussi [5,14]. Elle est en rapport avec une sténose pharyngo-oesophagienne [5].…”

Section: Discussionunclassified

“…Sur le plan carcinologique, les récidives éventuelles apparaissent en général dans les deux ans suivant l'intervention. Le taux d'échec locorégional après chirurgie radicale varie dans la littérature entre 20 à 66% [5,14]. Dans notre série, il est de 27%.…”

Section: Discussionunclassified

“…Le taux de métastases à distance n'est pas négligeable : 7% [5]. Le taux de survie à 5 ans varie entre 40 et 60% dans les cancers du larynx [4,9,14,15]. Dans notre étude, ce taux de 33% pourrait être amélioré avec la disponibilité des traitements adjuvats et le suivi régulier des patients.…”

Section: Discussionunclassified

See 4 more Smart Citations

Résultats carcinologiques et fonctionnels des laryngectomies pour cancer du larynx à l’Hôpital Principal de Dakar

Ca¹,

Loum²,

Diallo³

et al. 2021

Af J Oncol

View full text Add to dashboard Cite

INTRODUCTION: Delay in the diagnosis of cancers of the larynx affects the prognosis and often requires very mutilating surgery. AIM: To report the oncologic and functional outcomes of surgery for laryngeal cancers to Hôpital Principal de Dakar in Senegal. MATERIALS AND METHODS: This was a single-center retrospective study carried out from January 2009 to December 2014 in the ENT and head and neck surgery department including adult patients treated for curative surgery. RESULTS: Fifty patients were treated for laryngeal cancer. Thirty-seven of them underwent a laryngectomy. Lesions classified as cT2 represented 14%, and 16% were classified as cT1. Squamous cell carcinomas represented more than 97% of cases (36/37). Radiotherapy had completed the surgery in only 11 cases with an average delay of 2.75 months. Functionally, swallowing disorders were found in two patients with two cases of pharyngo-esophageal stenosis. On the carcinologic level, six patients presented a progression while four had tumor or lymph node recurrence. One patient showed lung metastasis. Overall survival at 7 years was 33%. CONCLUSION: The functional damage in laryngeal cancer surgery is significant and on the carcinologic level the results, although satisfactory, can be improved with a better availability of adjuvant treatments.

show abstract

Section: Discussionunclassified

See 3 more Smart Citations

Résultats carcinologiques et fonctionnels des laryngectomies pour cancer du larynx à l’Hôpital Principal de Dakar

Ca¹,

Loum²,

Diallo³

et al. 2021

Af J Oncol

View full text Add to dashboard Cite

show abstract

Analysis of local, regional, and distant recurrence of disease in mucoepidermoid tumors of larynx: A systematic review

Chiari,

Di Martino,

Caporale

et al. 2024

Head & Neck

View full text Add to dashboard Cite

The aim of this systematic review is to analyze epidemiology, clinical presentation, histopathological features, treatment and oncological outcomes in laryngeal mucoepidermoid cancer (MEC) in order to improve the knowledge on the management of such a rare malignant neoplasm. Specifically, authors highlight patients' and tumors' features about local, regional, and distant recurrence of disease. PRISMA 2020 guidelines were applied in this systematic literature review. A computerized search was performed using the Embase/Pubmed, Scopus, and Cochrane databases, for articles published from 1971 to December 2023. A descriptive and univariate analysis including selected papers with low or intermediate risk of bias was performed. Twenty‐seven papers (11 case series and 16 case reports) were included in this review. Fifty‐six patients were included in the analyses, with a mean age of 56.7 years; 84% of them were males. Most patients (86%) underwent a primary surgical approach. Clinical stage was reported as follows: early stage (26 patients) and locally advance and advanced stage (19 patients). Overall survival (OS) and disease‐free survival (DFS) at 2 years was 80% and 78%, respectively. The mean time to local recurrence was 18.7 months (range 8–36 months). The survival after recurrence is about 85% and 70% at 5 years, respectively. The mean time of lymph node recurrence was 14.7 months (range 7–19 months). Finally, the mean time of distant recurrence was 15 months (range 7–36 months) with a poor prognosis: all patients died due to the disease in a range of 0–7 months after metastasis evidence. Laryngeal MEC is a rare neoplasm of minor salivary glands in the larynx. No guidelines or indications about the management of this neoplasm are reported in the literature. The lower incidence of regional recurrence of the disease and the better OS and DFS underline how the prognosis of MEC is more favorable respect to other malignant histotypes.

show abstract

Total Laryngectomy

Wierzbicka

Jackowska

2022

Textbook of Surgery of Larynx and Trachea

View full text Add to dashboard Cite

Oncological and Functional Outcomes of Primary and Salvage Total Laryngectomy

Cited by 9 publications

References 13 publications

Résultats carcinologiques et fonctionnels des laryngectomies pour cancer du larynx à l’Hôpital Principal de Dakar

Résultats carcinologiques et fonctionnels des laryngectomies pour cancer du larynx à l’Hôpital Principal de Dakar

Analysis of local, regional, and distant recurrence of disease in mucoepidermoid tumors of larynx: A systematic review

Total Laryngectomy

Contact Info

Product

Resources

About