Oncologic Results of Retroperitoneoscopic Versus Open Surgery for T2 Upper Tract Urothelial Carcinoma

Shan, Hongli; Wang, Xiaoqing; Sun, Qingnian; Chen, Qihui; Xu, Bo; Hao, Yuanyuan; Xu, Wei

doi:10.1016/j.clgc.2015.05.011

Cited by 3 publications

(4 citation statements)

References 32 publications

(32 reference statements)

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“…Radical nephroureterectomy with bladder cuff excision is the standard treatment for UTUC, regardless of surgery approach (open or laparoscopic) [23][24][25][26]. Seisen et al recommended kidney-sparing management as a treatment option for patients with low-risk tumors [27,28].…”

Section: Discussionmentioning

confidence: 99%

Clinicopathologic characteristics and prognosis of upper tract urothelial carcinoma complicated with aristolochic acid nephropathy after radical nephroureterectomy

Shan

Tian

Hong

et al. 2020

BMC Complement Med Ther

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Background The purpose of this study was to identify the clinicopathologic characteristics and prognosis of upper tract urothelial carcinoma (UTUC) patients complicated with aristolochic acid nephropathy(AAN) after radical nephroureterectomy (RNU). Methods The clinical data of 42 UTUC patients with AAN (AAN group) and 238 UTUC patients without AAN (Non-AAN group) were retrospectively reviewed. All patients received a RNU with excision of bladder cuff. Demographic and clinical data, including preoperative indexes, intraoperative indexes and surgical outcomes were compared. Results There were no significant differences in age, tumor location, surgery approach, tumor pathologic grade, stage, the mean operative time and estimated blood loss between the two groups (all p > 0.05). There were more female patients in the AAN group (p < 0.001), and 57.1% were high grade tumors. The AAN group showed a higher complications rate (p = 0.003). The median follow-up time was 43.2 months. The AAN group showed a worse estimated 5-year overall survival rate (35.1% vs. 63.0%, p = 0.014), however, no significant difference was found between the two groups with regard to disease specific survival (63.5% vs. 81.5%, p = 0.091). Multivariate binary logistic regression analysis showed that AAN was an independent factor related with overall and disease specific survival. 38.9% of all patients experienced any types of recurrence, and the estimated 5-year recurrence-free survival rate was lower in the AAN group (37.1% vs. 63.7%, p = 0.001). In the comparison of subgroups stratified by recurrence type, the AAN group had a higher intravesical (p = 0.030) and contralateral recurrence rate (p = 0.040). Conclusion UTUC with AAN occurred more frequently in female patients who were more likely to develop high-grade tumors. However, these patients showed a worse overall survival and a lower recurrence-free survival rate than the other patients. AA-related UTUC might be associate with an increased risk of intravesical and contralateral recurrence after RUN.

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Section: Discussionmentioning

confidence: 99%

Clinicopathologic characteristics and prognosis of upper tract urothelial carcinoma complicated with aristolochic acid nephropathy after radical nephroureterectomy

Shan

Tian

Hong

et al. 2020

BMC Complement Med Ther

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“…Only one prospective RCT was reported [9]. The retrospective series were multicentre studies [22,23,34,41,44,49] and single-centre studies [5,[13][14][15][16][17][18][19][20][21][24][25][26][27][28][29][30][31][32][33][35][36][37][38][39][40]42,43,[45][46][47][48]50,51] in six and 34 cases, respectively. Most studies had small sample sizes (only six studies included over 100 patients in each treatment arm [34,41,44,[49][50][51]).…”

Section: Characteristics Of Included Studiesmentioning

confidence: 99%

“…Seven studies reported the oncological outcomes of hand-assisted laparoscopic versus open RNU [5,15,16,21,22,29,35], 33 studies compared laparoscopic with open RNU [9,13,14,[17][18][19][20][23][24][25][26][27][28][30][31][32][33][34][36][37][38][39][40][41][42][43][44][45][47][48][49][50][51], and one study compared both laparoscopic and hand-assisted laparoscopic RNU with open RNU [46]. No studies compared the oncological outcomes of robotic RNU with those of open RNU.…”

Section: Surgical Techniquesmentioning

confidence: 99%

“…Laparoscopic RNU was performed through a transperitoneal route in 14 studies [5,9,13,15,[24][25][26][35][36][37]39,41,48,50], through a retroperitoneal route in 13 studies [14,16,[18][19][20]23,26,28,29,31,32,47,51], and through either a transperitoneal or a retroperitoneal route in four studies [37,42,43,49]. The other studies did not report the route that was used (ie, transperitoneal or retroperitoneal).…”

Section: Surgical Techniquesmentioning

confidence: 99%

See 1 more Smart Citation

Oncological Outcomes of Laparoscopic Nephroureterectomy Versus Open Radical Nephroureterectomy for Upper Tract Urothelial Carcinoma: An European Association of Urology Guidelines Systematic Review

Peyronnet

Seisen

Dominguez-Escrig

et al. 2019

European Urology Focus

121

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Single Versus Maintenance Intravesical Chemotherapy for the Prevention of Bladder Recurrence after Radical Nephroureterectomy for Upper Tract Urothelial Carcinoma: A Randomized Clinical Trial

Harraz

Elshabrawy

El-Nahas

et al. 2019

Clinical Genitourinary Cancer

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Oncologic Results of Retroperitoneoscopic Versus Open Surgery for T2 Upper Tract Urothelial Carcinoma

Cited by 3 publications

References 32 publications

Clinicopathologic characteristics and prognosis of upper tract urothelial carcinoma complicated with aristolochic acid nephropathy after radical nephroureterectomy

Clinicopathologic characteristics and prognosis of upper tract urothelial carcinoma complicated with aristolochic acid nephropathy after radical nephroureterectomy

Oncological Outcomes of Laparoscopic Nephroureterectomy Versus Open Radical Nephroureterectomy for Upper Tract Urothelial Carcinoma: An European Association of Urology Guidelines Systematic Review

Single Versus Maintenance Intravesical Chemotherapy for the Prevention of Bladder Recurrence after Radical Nephroureterectomy for Upper Tract Urothelial Carcinoma: A Randomized Clinical Trial

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