2021
DOI: 10.1007/s13760-021-01761-8
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Oncologic causes of oculopalatal tremors: neurophysiology and treatment

Abstract: Oculopalatal tremor (OPT) is an acquired pathology characterized by continuous and rhythmical soft palatal movements combined with pendular nystagmus. Aside from vascular lesions, oncological masses affecting the dentatorubro-olivary pathway can impair brainstem and/or cerebellar pathways, manifesting as dyssynchronous movement. In this review, we delve into the neurophysiology of OPT along with oncological causes and treatment options based on the most recent clinical trial data. This literature review includ… Show more

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Cited by 3 publications
(2 citation statements)
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“…However, even with synchronization, the output of the inferior olivary nucleus is too small to induce ocular oscillations. For the weak oscillations emanating from the inferior olivary nucleus to become clinically visible and symptomatic, they to be amplified by the cerebellar cortex 20 . OPM results from a dual mechanism: ignition of a generator, the inferior olivary pacemaker, followed by an amplification/modulation by the cerebellum.…”
Section: Manuscriptmentioning
confidence: 99%
“…However, even with synchronization, the output of the inferior olivary nucleus is too small to induce ocular oscillations. For the weak oscillations emanating from the inferior olivary nucleus to become clinically visible and symptomatic, they to be amplified by the cerebellar cortex 20 . OPM results from a dual mechanism: ignition of a generator, the inferior olivary pacemaker, followed by an amplification/modulation by the cerebellum.…”
Section: Manuscriptmentioning
confidence: 99%
“…It has a positive effect on improving patients' prognosis, preventing disease recurrence, improving quality of life and reducing the burden on patients and their families. The Triangle Chronic Disease Tiered Management Model was developed by Kaiser Permanente, a large managed care organization in California, and has been used since 2002 to manage the care of patients with chronic diseases (9,10). The model divides patients into high-risk, moderaterisk, and stable tiers, and then provides specialized medical care proportional to the needs of each tier, creating a pyramidal tiered management model that is more economical and The model is a pyramidal hierarchical management model that treats patients more economically and effectively (11).…”
Section: Prefacementioning
confidence: 99%