“…However, the EpRE/ARE-activating protein does not activate the TRE consensus element. Overall, the conclusion that the response to monofunctional phase 2 enzyme inducers is mediated by AP-1 proteins (5,15,16,18,37) is clearly untenable in light of these and other results (13,20,21). Thus, it is crucial to identify the proteins that specifically interact with the EpRE/ARE sequences and mediate the action of these inducers.…”