The unitary group U(n) has elements ε i ∈ π 2i+1 (U (n)) (0 i n − 1) of its homotopy groups in the stable range. In this paper we show that certain multi Samelson products of type ε i , ε j , ε k are non-trivial. This leads us to the result that the nilpotency class of the group of the self homotopy set [SU(n), SU(n)] is no less than 3, if 4 n. Also by the power of generalized Samelson products, we can see the further result that, for a prime p and an integer n = pk, nil[SU(n), SU(n)] (p) 3, if (1) p 7 or (2) p = 5 and n ≡ 0 or 1 mod 4.