On What Time Scale Does Solvent Relaxation in Phospholipid Bilayers Happen?

Sýkora, Jan; Kapusta, P.; Fidler, and Vlastimil; Hof, Martin

doi:10.1021/la011337x

Cited by 112 publications

(139 citation statements)

References 10 publications

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“…So far, the membrane/water interface has been extensively studied by various techniques. [4][5][6][7][8][9][10][11] These previous works have shown that the water molecules adjacent to a membrane strongly interact with the headgroups and give significant influence on its mechanical strength and fluidity. [12][13][14] However, molecular-scale origin for such a grave influence has remained elusive.…”

mentioning

confidence: 99%

Spatial Distribution of Lipid Headgroups and Water Molecules at Membrane/Water Interfaces Visualized by Three-Dimensional Scanning Force Microscopy

et al. 2012

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At biological interfaces, flexible surface structures and mobile water interact with each other to present non-uniform three-dimensional (3D) distributions. In spite of their impact on the biological functions, molecular-scale understanding of such phenomena has remained elusive. Here we show direct visualization of such interfacial structures with subnanometer-scale resolution by 3D scanning force microscopy (3D-SFM). We measured a 3D force distribution at an interface between a model biological membrane and buffer solution by scanning a sharp tip within the 3D interfacial space. We found that vertical cross sections of the 3D image taken along a specific lateral direction shows characteristic molecular-scale contrasts tilted at 30 • † Membrane/Water Interfaces Visualized by 3D-SFM

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confidence: 99%

Spatial Distribution of Lipid Headgroups and Water Molecules at Membrane/Water Interfaces Visualized by Three-Dimensional Scanning Force Microscopy

et al. 2012

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“…groups have reported decay of Γ with time (t). 28,40 Qualitatively, this may explained as follows. At t = 0, the probe molecules in different environments are excited simultaneously.…”

Section: Model 2: Self-diffusion Of the Probementioning

confidence: 97%

On the origin of the anomalous ultraslow solvation dynamics in heterogeneous environments

Bhattacharyya

Bagchi

2007

J Chem Sci

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Many recent experimental studies have reported a surprising ultraslow component (even >10 ns) in the solvation dynamics of a polar probe in an organized assembly, the origin of which is not understood at present. Here we propose two molecular mechanisms in explanation. The first one involves the motion of the 'buried water' molecules (both translation and rotation), accompanied by cooperative relaxation ('local melting') of several surfactant chains. An estimate of the time is obtained by using an effective Rouse chain model of chain dynamics, coupled with a mean first passage time calculation. The second explanation invokes self-diffusion of the (di)polar probe itself from a less polar to a more polar region. This may also involve cooperative motion of the surfactant chains in the hydrophobic core, if the probe has a sizeable distribution inside the core prior to excitation, or escape of the probe to the bulk from the surface of the self-assembly. The second mechanism should result in the narrowing of the full width of the emission spectrum with time, which has indeed been observed in recent experiments. It is argued that both the mechanisms may give rise to an ultraslow time constant and may be applicable to different experimental situations. The effectiveness of solvation as a dynamical probe in such complex systems has been discussed.

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“…So far, the membrane-water interface has been extensively studied by various techniques [17,19,[100][101][102][103][104][105]. These previous works have shown that the water molecules adjacent to a membrane strongly interact with the headgroups and give significant influence on its mechanical strength and fluidity [106][107][108].…”

Section: Lipid-water Interfacementioning

confidence: 99%

Advanced Instrumentation of Frequency Modulation AFM for Subnanometer-Scale 2D/3D Measurements at Solid-Liquid Interfaces

Fukuma

2015

Noncontact Atomic Force Microscopy

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Since the first demonstration of true atomic-resolution imaging by frequency modulation atomic force microscopy (FM-AFM) in liquid, the method has been used for imaging subnanometer-scale structures of various materials including minerals, biological systems and other organic molecules. Rencetly, there have been further advancements in the FM-AFM instrumentation. Three-dimensional (3D) force measurement techniques are proposed for visualizing 3D hydration structures formed at a solid-liquid interface. These methods further enabled to visualize 3D distributions of flexible surface structures at interfaces between soft materials and water. Furthermore, the fundamental performance such as force sensitivity and operation speed have been significantly improved using a small cantilever and highspeed phase detector. These technical advancements enabled direct visualization of atomic-scale interfacial phenomena at 1 frame/sec. In this chapter, these recent advancements in the FM-AFM instrumentation and their applications to the studies on various interfacial phenomena are presented.

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On What Time Scale Does Solvent Relaxation in Phospholipid Bilayers Happen?

Cited by 112 publications

References 10 publications

Spatial Distribution of Lipid Headgroups and Water Molecules at Membrane/Water Interfaces Visualized by Three-Dimensional Scanning Force Microscopy

Spatial Distribution of Lipid Headgroups and Water Molecules at Membrane/Water Interfaces Visualized by Three-Dimensional Scanning Force Microscopy

On the origin of the anomalous ultraslow solvation dynamics in heterogeneous environments

Advanced Instrumentation of Frequency Modulation AFM for Subnanometer-Scale 2D/3D Measurements at Solid-Liquid Interfaces

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