On triazoles XI 11For Part X. see K. Esses-Reiter and J. Reiter, J. Heterocyclic Chem ( in press). structure elucidation of isomeric 1,2,4-triazolopyrimidinones

Fluorinated 1,2,4‐Triazolo[1,5‐a]pyrimidine‐6‐carboxylic Acid Derivatives as Antimycobacterial Agents

“…Refluxing with diethoxymethylenemalonate (DEEM) 2 in glacial acetic acid afforded 7-oxo-2-(trifluoromethyl)-4,7-dihydro-1,2,4-triazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester 3. Alkylation of the resulting ester at the N-4 position with alkyl / aralkyl halides (5a -e) in dry DMF and NaH as a base afforded compounds 6a -e in accordance with previous reports on the alkylation of 1,2,4-triazolo [1,5-a]pyrimidines [15,16]. Base-catalyzed hydrolysis of ethyl esters 3, and 6a -e using sodium hydroxide afforded compounds 4 and 7a -e, respectively.…”

Monte Carlo studies of static properties of interacting lattice polymers with the cooperative‐motion algorithm

“…Fig. 8 is a plot of the simulated distribution compared to the very simple result (16). The picture shows that our data points match almost perfectly the simple mean-field result.…”

7-Ethoxycarbonylmethyl-5-methyl-1,2,4-triazolo[1,5-a]pyrimidine

“…In the literature, several reports have been devoted to the synthesis of 1,2,4-triazolopyrimidines using other 1,3-difunctional synthons (Shaban & Nasr, 1990;Reiter, Pougo & Dvortsak, 1987;Moute, Kleschick, Meikle & Snider, 1989;Kuenstlinger & Breitmaier, 1983). Usual analytical and spectroscopic techniques do not permit identification of the isomeric compounds (3) and (4), and so, in order to …”