2003
DOI: 10.1034/j.1600-0420.81.s237.1.x
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On the structural origin of refractive instability and corneal haze after excimer laser keratectomy for myopia

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Cited by 15 publications
(11 citation statements)
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“…These findings in rabbits provide a structural explanation for the clinically observed lack of post-LASIK wound healing that allows the corneal flap to be separated from its stromal bed for an indeterminate time after surgery. 4 5 Since the rabbit cornea otherwise is known to heal aggressively (following, for example, photorefractive keratectomy or a penetrating wound), [36][37][38] LASIK provides an interesting model for studying the basic regulation of corneal wound repair and the development of fibrosis. Further insight into these important aspects is required to improve the outcome of LASIK and other corneal refractive surgical procedures.…”
Section: Discussionmentioning
confidence: 99%
“…These findings in rabbits provide a structural explanation for the clinically observed lack of post-LASIK wound healing that allows the corneal flap to be separated from its stromal bed for an indeterminate time after surgery. 4 5 Since the rabbit cornea otherwise is known to heal aggressively (following, for example, photorefractive keratectomy or a penetrating wound), [36][37][38] LASIK provides an interesting model for studying the basic regulation of corneal wound repair and the development of fibrosis. Further insight into these important aspects is required to improve the outcome of LASIK and other corneal refractive surgical procedures.…”
Section: Discussionmentioning
confidence: 99%
“…The small amount of scattered light produced by this tissue has in particular been extensively researched in the literature [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20]. All previous theories explaining corneal transparency [21][22][23][24][25][26][27] have focused on light propagation in the stromal extracellular matrix.…”
Section: Introductionmentioning
confidence: 99%
“…Smaller organelles, such as mitochondria and endoplasmic reticulum, are likely responsible for scattering at larger angles. Møller-Pedersen [10,11] studied these particular unclear aspects. McCally et al [8] presented the first measurements of light-scattering and their link to the ultrastructure of scars.…”
Section: Introductionmentioning
confidence: 99%
“…For example, the creation of a lamellar flap during the LASIK procedure increases the risk of intraoperative complications, such as irregular cuts, epithelial ingrowth, and infectious keratitis [2,3]. Postoperative scarring and haze is more common after PRK than LASIK [4].…”
Section: Introductionmentioning
confidence: 99%