Abstract. This article discusses modern techniques for nonuniform sampling and reconstruction of functions in shift-invariant spaces. It is a survey as well as a research paper and provides a unified framework for uniform and nonuniform sampling and reconstruction in shiftinvariant spaces by bringing together wavelet theory, frame theory, reproducing kernel Hilbert spaces, approximation theory, amalgam spaces, and sampling. Inspired by applications taken from communication, astronomy, and medicine, the following aspects will be emphasized: (a) The sampling problem is well defined within the setting of shift-invariant spaces. (b) The general theory works in arbitrary dimension and for a broad class of generators. (c) The reconstruction of a function from any sufficiently dense nonuniform sampling set is obtained by efficient iterative algorithms. These algorithms converge geometrically and are robust in the presence of noise. (d) To model the natural decay conditions of real signals and images, the sampling theory is developed in weighted L p -spaces.