On the source of the quasi Carrington Rotation periodic magnetic
variations on the Martian surface: InSight Observations and
Modelling

Luo, Hao; Du, Aimin; Zhang, S. H.; Ge, Yasong; Zhang, Y.; Sun, Songlin; Zhao, Lulu; Lei, Tian; Li, and S. Y.

doi:10.26464/epp2022022

Cited by 4 publications

(2 citation statements)

References 33 publications

(58 reference statements)

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“…Among the 34 cases included in this study, 15 have been previously reported, and their treatments and outcomes were updated. (3,(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17) There is one patient enrolled in this study lack updated information, thus some denominator of proportion calculation are 33 in this article. Data on surviving patients were updated during the study period of more than two years.…”

Section: Study Cohortmentioning

confidence: 99%

“…(3,4) To date, 15 patients with NUP98::RARG, PML::RARG, CPSF6::RARG, NPM1::RARG, and HNRNPc::RARG fusions have been reported. (3,(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17) All these patients showed strikingly similar features to those of acute promyelocytic leukemia (APL), including clinical presentation and the leukemic cells' cytomorphological and immunophenotypical features. However, these patients showed no response to standard treatment with all-trans retinoic acid (ATRA) and arsenic trioxide (ATO) and had poor outcomes.…”

Section: Introductionmentioning

confidence: 99%

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A global study for acute myeloid leukemia with RARG rearrangement

et al. 2023

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Acute myeloid leukemia (AML) with RARG rearrangement has clinical, morphologic, and immunophenotypic features similar to classic acute promyelocytic leukemia. However, AML with RARG rearrangement is insensitive to all-trans retinoic acid (ATRA) and arsenic trioxide (ATO) and carries a poor prognosis. We initiated a global cooperative study to define the clinicopathological features, genomic and transcriptomic landscape, and outcomes of AML with RARG rearrangements collected from 29 study groups/institutions worldwide. Thirty-four AML with RARG rearrangements were identified. Bleeding or ecchymosis was present at 18 (54.5%) patients. Morphology diagnosed as M3 and M3v accounted for 73.5% and 26.5% of cases, respectively. Immunophenotyping showed following characteristics: positive for CD33, CD13, and MPO but negative for CD38, CD11b, CD34, and HLA-DR. Cytogenetics showed normal karyotype in 38% and t(11;12) in 26% of patients. The partner genes of RARG were diverse and included CPSF6 (n=14), NUP98 (n=11), HNRNPc (n=6), HNRNPm (n=1), PML (n=1), and NPM1 (n=1). WT1- and NRAS/KRAS-mutations were common co-mutations. None of the 34 patients responded to ATRA and/or ATO. Death within 45 days from diagnosis occurred in 10 patients (~29%). At the last follow-up, 23 patients had died, and the estimated 2-year cumulative incidence of relapse, event-free survival, and overall survival were 68.7%, 26.7%, and 33.5%, respectively. Unsupervised hierarchical clustering using RNA-seq data from 201 AML patients showed that 81.8% of the RARG fusion samples clustered together, suggesting a new molecular subtype. RARG rearrangement is a novel entity of AML that confers a poor prognosis.

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Section: Study Cohortmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

A global study for acute myeloid leukemia with RARG rearrangement

et al. 2023

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Along-track Calibration of the Zhurong Rover Magnetometer

Luo,

Du,

et al. 2024

Sci. China Earth Sci.

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Comparison of the Ionospheric Dynamo Current of Mars Above InSight and Zhurong Landing Sites: A Modeling Study

Luo,

Tian,

et al. 2024

JGR Space Physics

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Previous observational studies suggest that the surface time‐varying magnetic field of Mars originates in large part from the dynamo currents in the Martian ionosphere. However, whether there are significant differences in the strength, configuration, diurnal, and seasonal variations of the dynamo currents above different regions need to be further studied. In this study, using the ionospheric parameters from Mars Climate Database version 5.3 (MCD v5.3) and 7 years of MAVEN magnetic field measurements, we compare the ionospheric dynamo currents above the landing sites of InSight (4.50°N, 135.62°E) and Zhurong (25.07°N, 109.90°E) and the resulting surface magnetic variations at the two landing sites by conducting a modeling study. We find that the average dynamo current as well as its diurnal magnetic field amplitude on the Martian surface is significantly stronger at InSight than that at Zhurong due to the stronger background magnetic field strength and more perpendicular angle between magnetic field and neutral wind vectors in the dynamo region, though the conductivities is always weaker over InSight landing site. The seasonal variation of the current intensity (represented by differences between northern winter and summer solstices) is prominent over InSight than that over Zhurong because the heliospheric distance effect‐resulted conductivity difference is the dominate factor for the seasonal variations over InSight while both the heliospheric distance and solar zenith angle (SZA) contribute to the current intensity at different Ls over Zhurong. The two factors partially offset each other and lead to a smaller seasonal variation. The role of crustal field, as well as the latitude effects on dynamo currents is also discussed. This study provides an attempt to promote the understanding of the solar wind‐induced magnetosphere‐ionosphere‐surface coupling process.

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On the source of the quasi Carrington Rotation periodic magnetic variations on the Martian surface: InSight Observations and Modelling

Cited by 4 publications

References 33 publications

A global study for acute myeloid leukemia with RARG rearrangement

A global study for acute myeloid leukemia with RARG rearrangement

Along-track Calibration of the Zhurong Rover Magnetometer

Comparison of the Ionospheric Dynamo Current of Mars Above InSight and Zhurong Landing Sites: A Modeling Study

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