On the Prognostic Potential of the Sequential 123-I-HDA-Tomoscintigram After the First MI

Rösler, H; Noelpp, U.; Tóth, Tibor; Schubiger, P. A.; Hunziker, H

doi:10.1093/eurheartj/6.suppl_b.49

European Heart Journal

1985

DOI: 10.1093/eurheartj/6.suppl_b.49

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On the Prognostic Potential of the Sequential 123-I-HDA-Tomoscintigram After the First MI

H Rösler¹,

U. Noelpp²,

Tibor Tóth³

et al.

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1989

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Routine 18F-2-Deoxy-2-Fluoro-D-Glucose (18F-FDG) Myocardial Tomography Using a Normal Large Field of View Gamma-Camera

Höflin¹,

Ledermann²,

Noelpp³

et al. 1989

Angiology

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There is a recent need to study glucose metabolism of the heart in ischemic, as well as in "hibernating or stunned" myocardium, and compare it with that in perfusion studies. In non-positron emission tomography centers, positron imaging is possible with a standard Anger-type camera if proper collimation and adequate shielding of the camera crystal can be achieved. For the study with fast-decaying isotopes, seven-pinhole tomography (7PHT), a limited-angle method designed for transaxial tomography of the left ventricle using a nonrotating camera, is well suited, because projections are acquired simultaneously. Individual adjustment (patient supine) of the camera's view axis (CAx) with the left ventricular axis (LVAx) gives excellent results: sensitivity for CHD 82%, specificity 72% in a prospective 201TI study (48 patients, x-ray coronarography as reference). Good alignment of CAx with LVAx is also achieved with the patient prone in LAO in a hammock above the camera surface. In this setting additional lead shielding of the camera is possible using a table reinforced with 5 cm of lead with a central hole for the 7PH-collimator, which has a special lead inlay. This allows utilization of the 511 KeV emitter 18F-FDG, which with a half-life of 109 minutes, can be transported a reasonable distance from the production site. System sensitivity and resolution for 18F was found comparable to 201Tl, 99mTc, and 123I using a phantom. First clinical examinations after 201Tl stress/redistribution studies showed increased 18F-FDG uptake in ischemic heart segments, as well as in "hibernating" nonperfused or "stunned" myocardium.

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Routine 18F-2-Deoxy-2-Fluoro-D-Glucose (18F-FDG) Myocardial Tomography Using a Normal Large Field of View Gamma-Camera

Höflin¹,

Ledermann²,

Noelpp³

et al. 1989

Angiology

View full text Add to dashboard Cite

show abstract

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On the Prognostic Potential of the Sequential 123-I-HDA-Tomoscintigram After the First MI

Cited by 1 publication

References 9 publications

Routine 18F-2-Deoxy-2-Fluoro-D-Glucose (18F-FDG) Myocardial Tomography Using a Normal Large Field of View Gamma-Camera

Routine 18F-2-Deoxy-2-Fluoro-D-Glucose (18F-FDG) Myocardial Tomography Using a Normal Large Field of View Gamma-Camera

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