On the possibility of controlling the hydrophilic/hydrophobic characteristics of toroid Mo138 nanocluster polyoxometalates

Physicochemical and biochemical properties of the Keplerate-type nanocluster polyoxomolybdates as promising components for biomedical use

“…The Keplerate-type POMs and alike, being hydrophilic particles, are able to associate (form conjugates) in their external sphere with diverse substances, which include surfactants (SAs) of various nature [164][165][166][167][168][169][170][171], dyes, photosensitizers [109,110,[172][173][174], and polymers [174][175][176][177][178][179], mainly water-soluble ones. POMs functionalization makes it possible to selectively influence their hydrophilic and hydrophobic properties [110], create catalytic and photocatalytic systems with adjustable characteristics, as well as compositions for targeted delivery in biomedicine, controlled by an electric [179] or magnetic field [180,181]. The hydrophobized POMs acquire an ability to more actively interact with molecules of nonpolar substances and adsorb them [110].…”

“…POMs functionalization makes it possible to selectively influence their hydrophilic and hydrophobic properties [110], create catalytic and photocatalytic systems with adjustable characteristics, as well as compositions for targeted delivery in biomedicine, controlled by an electric [179] or magnetic field [180,181]. The hydrophobized POMs acquire an ability to more actively interact with molecules of nonpolar substances and adsorb them [110]. There appears a possibility of formation of ionic associates based on POM and cations of metals (alkaline earths, rare earths, transition metals, including luminescent labels and magnetic resonance imaging (MRI) tags [19,[121][122][123]), and of cationic surfactants.…”

“…The discovered POM stabilization in associates with calcium will be discussed below. It is important to note the ability of the Keplerate and compositionally similar toroidal [88][89][90][91]110] POMs to self-association in solutions, i.e., to self-assembly into hollow single-walled globules (Fig. 4) [91,199], the diameter of which can vary from tens to hundreds of nanometers, depending on concentration, acidity, and dielectric permittivity of the medium [199].…”

“…for Mo 132 and Mo 72 Fe 30 , respectively. The POMs capable, in principle, of changing the energy state of molecules included in their cavity, are considered promising catalytic materials in reactions of fine organic synthesis, membrane technologies, and sensorics[101][102][103][104][105][106][107][108][109][110][111][112][113]. FIG…”

Tetrahedral Keggin Core Tunes the Visible Light-Assisted Catalase-Like Activity of Icosahedral Keplerate Shell

“…Structurally well-defined porous spherical metal oxide-based inorganic nanocapsules of type {(M VI ) M 5 VI } 12 (linker) 30 (M = Mo or W) called Keplerates have been vastly investigated in several novel phenomena and are the basis of many invaluable applications due to their unique structural features. − Among them, {Mo 72 Fe 30 } nanoclusters, consisting of 12 pentagonal molybdenum oxide units linked by 30 Fe aq 3+ centers, have received much attention because of attractive applications in medicine and biology − and diverse structures. They can be formed by replacing 30 Mo 2 O 4 Ac linkers in {Mo 132 } with 30 Fe aq 3+ in crystalline forms including discrete molecules, interconnected one-dimensional chains, or two-dimensional layers. , They can also be prepared directly by mixing acidic solutions of FeCl 3 and NaMoO 4 , producing immediately an amorphous phase of cluster .…”