On the origins of the semen analysis: A close relationship with the history of the reproductive medicine

Andrade-Rocha, Fernando Tadeu

doi:10.4103/jhrs.jhrs_97_17

Cited by 19 publications

(8 citation statements)

References 36 publications

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“…The decline in semen quality over the past few decades might explain the increased trend in male infertility research [1, 2, 37], as reported in our previous bibliometric study [27]. Semen analysis has been the routine test for the evaluation of male fertility potential since the first half of the twentieth century and has not overcome its limitations of being subjective and poor standardization [3, 38]. In addition, 10 to 30% of infertile patients are inexplicably normozoospermic [39].…”

Section: Discussionmentioning

confidence: 99%

Tracking research trends and hotspots in sperm DNA fragmentation testing for the evaluation of male infertility: a scientometric analysis

Baskaran

Agarwal

Selvam

et al. 2019

Reprod Biol Endocrinol

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BackgroundThis article describes the research trends in sperm DNA fragmentation (SDF) over the past 20 years (1999–2018) using a scientometric approach.MethodsA stepwise approach was adopted to retrieve scientometric data (articles per year, authors, affiliations, journals, countries) from Scopus and analyze the publication pattern of SDF with reference to key areas of research in the field of Andrology.ResultsA total of 2121 articles were retrieved related to SDF. Our data revealed an increasing research trend in SDF (n = 33 to n = 173) over the past 20 years (R2 = 0.894). Most productive country in publications was the USA (n = 450), while Agarwal A. (n = 129) being the most productive author. Most of the articles in SDF were primarily focused on lifestyle (n = 157), asthenozoospermia (n = 135) and varicocele (130). Mechanistic studies on SDF were published twice as much as prognostic/diagnostic studies, with significant emphasis on oxidative stress. Terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) was the most widely used technique to evaluate SDF. Publications on SDF related to assisted reproductive techniques also showed a linear increasing trend (R2 = 0.933).ConclusionsOur analysis revealed an increasing trend in SDF publications predominantly investigating lifestyle, asthenozoospermia and varicocele conditions with TUNEL being the most widely used technique. A substantial increase in research is warranted to establish SDF as prognostic/diagnostic parameter to evaluate clinical scenarios and ART outcomes.

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Section: Discussionmentioning

confidence: 99%

Tracking research trends and hotspots in sperm DNA fragmentation testing for the evaluation of male infertility: a scientometric analysis

Baskaran

Agarwal

Selvam

et al. 2019

Reprod Biol Endocrinol

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“…Establishment of certain values for semen in order to predict chances of conception generates the need of references for male fertility. Requirement for semen analysis and semen parameters have been set as recommended in successive editions of WHO in 1980WHO in , 1987WHO in , 1992WHO in , 1999 and 2010 [1]. The following table [69] represents changes for cut off values for semen parameters according consecutive WHO manuals:…”

Section: Sperm Sample Evaluation and Referencesmentioning

confidence: 99%

“…The link between semen quality and fertility has been studied in humans since 1930 [1]. Semen analysis, as a standard laboratory test, gives basic information on spermatogenesis, secretory activity of the gonads and patency of the male genital tract [2].…”

Section: Introductionmentioning

confidence: 99%

The Sperm: Parameters and Evaluation

Milachich¹,

Dyulgerova-Nikolova²

2020

Innovations in Assisted Reproduction Technology

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Sperm abnormalities are a major factor of human infertility. Since 1987, there are several references in different editions of World Health Organization (WHO) manual defining optimal sperm parameters. Over the years, many reproductive specialists have been constantly debating, suggesting and remodeling the frame values in those guidelines. Semen parameters have a leading role both in natural conception and assisted reproduction technologies (ART) outcomes. Deviations expressed in lower sperm count, impaired motility, abnormal morphology, and high percentage of sperm DNA fragmentation are linked to reduced chances to achieve pregnancy. In cases with low sperm count, severe oligoasthenozoospermia (OA) or azoospermia, karyotyping or evaluation with sperm aneuploidy test (SAT) could be an option and genetic counseling will be necessary if there is an obvious deviation or aberration (e.g., translocation, aneuploidy, etc.). Taking care of lifestyle factors as body mass index (BMI), diets, alcohol intake, smoking, using some additional nutrition and vitamin supplements might affect sperm parameters and contribute to the chances of a couple to conceive.

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“…The relationship between semen quality and fertility has been documented in humans since 1930. 1 Clinical estimation of semen parameters is usually confined to evaluate semen volume, sperm concentration, sperm motility, as well as sperm morphology. However, the predictive values regarding these factors are limited even after the introduction of standardized methods for semen analysis.…”

Section: Introductionmentioning

confidence: 99%

Assessment of seminal calcium and magnesium levels in infertile men with varicocele before and after varicocelectomy

et al. 2021

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Background: Trace elements perform a vital role in all stages of human physiology, as well as reproduction.Objective: This study aimed to assess seminal calcium (Ca) and magnesium (Mg) in infertile men associated with varicocele (Vx). Materials and methods:Overall, 50 men were divided into two groups: fertile men (n = 20) and infertile men who were scheduled for Vx surgical repair (n = 30). Exclusion criteria were as follows: azoospermia, smoking, leukocytospermia, and consumption of Ca and/or Mg supplements. All cases were subjected to history taking and clinical examination. Semen analysis and assessment of seminal Ca and Mg by the colorimetric method were carried out for all cases at the base point and 3 months postvaricocelectomy.Results: Generally, the mean seminal Ca and Mg levels demonstrated significant decreases in infertile men with Vx compared with the healthy fertile men linked to higher Vx grade as well as Vx bilaterality. These seminal decreases demonstrated significant increases after Vx surgical repair. Collectively, seminal Ca and Mg levels showed a significant positive correlation (r = 0.665, p= 0.001).

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On the origins of the semen analysis: A close relationship with the history of the reproductive medicine

Cited by 19 publications

References 36 publications

Tracking research trends and hotspots in sperm DNA fragmentation testing for the evaluation of male infertility: a scientometric analysis

Tracking research trends and hotspots in sperm DNA fragmentation testing for the evaluation of male infertility: a scientometric analysis

The Sperm: Parameters and Evaluation

Assessment of seminal calcium and magnesium levels in infertile men with varicocele before and after varicocelectomy

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