On the occurrence of two “soluble” arylsulphatases in chicken liver

Fedecka-Bruner, Barbara; Croisille, Y

doi:10.1016/s0300-9084(78)80680-4

Cited by 4 publications

(5 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…2C). These findings are consistent with the histological observation that 8-9 d after beheading, total regression of the testes has occurred in D. lugubris (8). We also observed expression of the gene in the ovaries at 5 d of regeneration, and this expression was maintained until 7 d (Fig.…”

Section: Resultssupporting

confidence: 91%

“…5). Moreover, there is a regression of the ovaries, testes, yolk glands, and copulatory apparatus during regeneration of sexual worms that has been described histologically in Bdellocephala brunnea (6,7) and Dugesia lugubris (8,9). In addition, most planarian species can undergo long periods of starvation, during which they are reduced from their normal adult size but maintain perfect scaling.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Gtdap-1 promotes autophagy and is required for planarian remodeling during regeneration and starvation

González‐Estévez

Felix

Aboobaker

et al. 2007

Proc. Natl. Acad. Sci. U.S.A.

View full text Add to dashboard Cite

Remodeling is an integral component of tissue homeostasis and regeneration. In planarians, these processes occur constantly in a simple tractable model organism as part of the animal's normal life history. Here, we have studied the gene Gtdap-1, the planarian ortholog of human death-associated protein-1 or DAP-1. DAP-1, together with DAP-kinase, has been identified as a positive mediator of programmed cell death induced by ␥-IFN in HeLa cells. Although the function of DAP-kinase is well characterized, the role of DAP-1 has not been studied in detail. Our findings suggest that Gtdap-1 is involved in autophagy in planarians, and that autophagy plays an essential role in the remodeling of the organism that occurs during regeneration and starvation, providing the necessary energy and building blocks to the neoblasts for cell proliferation and differentiation. The gene functions at the interface between survival and cell death during stress-inducing processes like regeneration and starvation in sexual and asexual races of planarians. Our findings provide insights into the complex interconnections among cell proliferation, homeostasis, and cell death in planarians and perspectives for the understanding of neoblast stem cell dynamics.autophagy ͉ cell death ͉ planarian ͉ homeostasis neoblast

show abstract

Section: Resultssupporting

confidence: 91%

mentioning

confidence: 99%

Gtdap-1 promotes autophagy and is required for planarian remodeling during regeneration and starvation

González‐Estévez

Felix

Aboobaker

et al. 2007

Proc. Natl. Acad. Sci. U.S.A.

View full text Add to dashboard Cite

show abstract

“…A sublethal dose of ␥-irradiation (10 Gy) also led to degeneration of the testes followed by their regeneration (37) in a time course similar to that shown for transverse amputation behind the ovaries (data not shown). In contrast to the regression and regeneration of the testes observed by morphological criteria (36,37) and by Tplastin in situ hybridization, expression of nanos mRNA persisted throughout the process of testes regression and regeneration after amputation (Fig. 3B) and sublethal doses of ␥-irradiation (data not shown).…”

Section: Resultsmentioning

confidence: 63%

nanos function is essential for development and regeneration of planarian germ cells

Wang

Zayas

Guo

et al. 2007

Proc. Natl. Acad. Sci. U.S.A.

184

257

View full text Add to dashboard Cite

Germ cells are required for the successful propagation of sexually reproducing species. Understanding the mechanisms by which these cells are specified and how their totipotency is established and maintained has important biomedical and evolutionary implications. Freshwater planarians serve as fascinating models for studying these questions. They can regenerate germ cells from fragments of adult tissues that lack reproductive structures, suggesting that inductive signaling is involved in planarian germ cell specification. To study the development and regeneration of planarian germ cells, we have functionally characterized an ortholog of nanos, a gene required for germ cell development in diverse organisms, from Schmidtea mediterranea. In the hermaphroditic strain of this species, Smed-nanos mRNA is detected in developing, regenerating, and mature ovaries and testes. However, it is not detected in the vast majority of newly hatched planarians or in small tissue fragments that will ultimately regenerate germ cells, consistent with an epigenetic origin of germ cells. We show that Smed-nanos RNA interference (RNAi) results in failure to develop, regenerate, or maintain gonads in sexual planarians. Unexpectedly, Smed-nanos mRNA is also detected in presumptive testes primordia of asexual individuals that reproduce strictly by fission. These presumptive germ cells are lost after Smed-nanos RNAi, suggesting that asexual planarians specify germ cells, but their differentiation is blocked downstream of Smed-nanos function. Our results reveal a conserved function of nanos in germ cell development in planarians and suggest that these animals will serve as useful models for dissecting the molecular basis of epigenetic germ cell specification.epigenesis ͉ germ cell specification ͉ RNA interference ͉ Schmidtea mediterranea ͉ Platyhelminthes

show abstract

“…In conclusion, our studies have indicated that chicken caecal arylsulphatase can be purified by chromatography on concanavalin A-and cyclic AMP-Sepharose. This arylsulphatase resembles arylsulphatases A of other avian (Farooqui & Bachhawat, 1971Ahmad et al, 1977;Fedecka-Bruner & Croisille, 1978) and mammalian (Roy, 1976;Dodgson & Rose, 1975;Farooqui, 1980;1981, 1987 tissues in its response to inhibition by sulphate and phosphate ions, its Mr and its glycoprotein nature. Further, like arylsulphatases A of other sources, chicken caecal enzyme hydrolyses cerebroside 3-sulphate (Mehl & Jatzkewitz, 1968;Farooqui & Bachhawat, 1972Porter et al, 1972).…”

Section: Discussionmentioning

confidence: 66%

“…Arylsulphatase C is involved in the degradation of steroid sulphates (Farooqui, 1980(Farooqui, , 1981(Farooqui, , 1987. Arylsulphatases have been extensively purified and characterized from various mammalian (Nichol & Roy, 1964;Stevens et al, 1975;Farooqui, 1976a;Farooqui & Roy, 1976;McGovern et al, 1982;Moriyasu et al, 1982) and avian (Farooqui & Bachhawat, 1972;Ahmad et al, 1977;Fedecka-Bruner & Croisille, 1978) tissues. However, little is known about these enzymes in intestinal tissues (Hsu & Tappel, 1964;Szafran & Szafran, 1963;Danovitch & Laster, 1969).…”

Section: Introductionmentioning

confidence: 99%

Comparison of arylsulphatases from Eimeria tenella (parasite) and chicken caecum (host)

Farooqui¹,

Hanson²

1987

Biochemical Journal

View full text Add to dashboard Cite

Chicken caecal arylsulphatase was purified 700-fold by (NH4)2SO4 fractionation, concanavalin A-Sepharose and cyclic AMP-Sepharose chromatographies. The purified enzyme was a glycoprotein of Mr 97,000. It hydrolysed p-nitrocatechol sulphate, cerebroside 3-sulphate and ascorbic acid 2-sulphate and was strongly inhibited by Na2SO4 (Ki = 50 microM) and Na3PO4 (Ki = 20 microM). Arylsulphatase from Eimeria tenella sporozoites was purified 28-fold by (NH4)2SO4 fractionation. Arylsulphatase of E. tenella sporozoites was not a glycoprotein. It had an Mr of 49,000. It was inhibited by Na2SO4 (Ki = 300 microM), sodium phosphate (Ki = 90 microM) and heparin. It hydrolysed ascorbic acid 2-sulphate, but cerebroside 3-sulphate was not desulphated. The kinetic parameters of chicken caecal arylsulphatase were different from those of the E. tenella enzyme.

show abstract

On the occurrence of two “soluble” arylsulphatases in chicken liver

Cited by 4 publications

References 27 publications

Gtdap-1 promotes autophagy and is required for planarian remodeling during regeneration and starvation

Gtdap-1 promotes autophagy and is required for planarian remodeling during regeneration and starvation

nanos function is essential for development and regeneration of planarian germ cells

Comparison of arylsulphatases from Eimeria tenella (parasite) and chicken caecum (host)

Contact Info

Product

Resources

About