Fe, and V; (2) elliptical in plan on the basis of a contour plot, and crosscuts the regional stratigraphic trends; (4) located on the edge of the Silurian evaporite basin; (5) associated with large-scale, northwesterly-trending LANDSAT lineaments; (6) localized on an intersection of a major northeasterly zone of right-lateral transcurrent faulting, and a northwesterly-trending zone of cross-faulting, fracturing, and jointing manifested by abrupt changes in strike of major structural elements; (7) between two large aeromagnetic highs, reflecting mafic basement rocks. (8) associated with gamma-ray anomalies in deep subsurface oil and gas well logs, and (8) associated with a linear zone of fluorine anomalies in water wells entering the area from the south parallel to the transcurrent faults and fold axes. At the regional scale (1:1,000,000) anomaly A is defined by a cluster of discrete titanium highs that coincide with a regional anomaly zone of cerium, lanthanum, thorium, iron, and manganese. Northeasterly-trending regional anomalies of lanthanum and thorium make a sharp departure to the northwest in the area of anomaly A, coinciding with crossfaults of like trend and deflection of fold axes. In detail, recontoured at a 1:500,000 scale, the circular clusters of regional titanium highs become a spectacularily high contrast, elliptical titanium pattern with a northwest-trending long axis of about 38 miles. Mafic-ultramafic igneous occurrences in the region could have affinities to anomaly A. (1) To the northeast in Pennsylvania, on structural alignment with anomaly A, mica peridotite dikes intrude the coal measure sequence. One of these occurrences at Masontown, Fayette County is dated at about 185 Ma. The second dike occurrence in the coal measure sequence at Dixonville, Pennsylvania has not been dated to our knowledge. Both occurrences in Pennsylvania are on the flanks of the Chestnut Ridge anticline, which also crosses anomaly A. (2) Several occurrences of northwesterly-trending alkalic mafic and felsic dikes of Jurassic to Eocene age are intruded into joint sets southeast of anomaly A in Pendleton County, West Virginia. This same structural trend crosses anomaly A. The many geological and geochemical similarities of anomaly A to the rift-related alkalic intrusions, carbonatites, and diatremes of the Illinois-Kentucky mining district, southeastern Missouri, and Magnet Cove, Arkansas leads us to conclude that the anomaly is due to a diatreme in the subsurface. We discuss several recommendations for follow-up investigation. Anomaly A warrants further investigation for possible diatreme-related mineralization (fluorite, sulfides, barite, REE, niobium, and tin, as well as Ti). The titanium distribution suggests that titanium minerals and associated REE minerals are being shed from bedrock near the upper reaches of tributary streams. Titanium and rare earth-bearing minerals are then distributed down-drainage to form placers at stream confluences, and in downstream areas where gradient flattens.