On the Occurrence and Fine Structure of an Appendage in Human and Murine Erythrocytes

Miyoshi, Masayuki; Matsukura, Yutaka

doi:10.1679/aohc1950.31.55

Cited by 2 publications

(2 citation statements)

References 4 publications

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“…The wart-like elevations of the normal erythrocytes shown in the present study very likely correspond to the projections observed by MIYOSHI and MATSUKURA (1969) in their transmission electron microscope study of sectioned human and murine erythrocytes (fixation in 2.5% glutaraldehyde).…”

Section: Surface Structure Of Normal Erythrocytessupporting

confidence: 87%

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Scanning Electron Microscopy of Normal and Pathological Human Erythrocytes

Tokunaga

Fujita

Hattori

1969

Arch. Histol. Jap., Arch. Histol. Jpn

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The first scanning electron micrograph of erythrocytes seems to be that of PEASE and HAYES published in 1966. More advanced and detailed studies were made by CLARKE and SALSBURY (1967) and CLARKE (1967, see also CLARKE, SALSBURY and ROWLAND, 1968). These authors observed under the scanning electron microscope not only normal human erythrocytes but also pathological forms, e. g., red cells showing patchy denudation of the cell membrane after splenectomy, target cells and other irregular forms in thalassemia major, and typical deformities in sickle cell anemia, hereditary elliptocytosis and other hematological diseases.The present paper attempts a methodological analysis for the application of scanning electron microscopy to hematology with special reference to the osmotic effects of fixation, which has been performed by none of the previous authors as far as is known. It further aims to describe the detailed surface structure of normal human erythrocytes and their changes in some pathological conditions such as elliptocytosis, spherocytosis and aplastic anemia.

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Section: Surface Structure Of Normal Erythrocytessupporting

confidence: 87%

“…These are believed to correspond to the segresome-like appendage seen in the transmission electron microscopy of sectioned erythrocytes (MIYOSHI and MATSUKURA, 1969 …”

Section: Discussionmentioning

confidence: 88%