On the Influence of Heart Rate and Coupling Interval Prematurity on Heart Rate Turbulence

Barquero-Pérez, Óscar; Figuera, Carlos; Goya–Esteban, Rebeca; Jiménez, Inmaculada; Gimeno-Blanes, Francisco-Javier; Laguna, Pablo; Martínez, Juan Pablo; Gil, Eduardo; Sörnmo, Leif; García‐Alberola, Arcadi; Rojo‐Álvarez, José Luis

doi:10.1109/tbme.2016.2554614

Cited by 5 publications

(2 citation statements)

References 20 publications

(29 reference statements)

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“…The VPC tachograms [5], so apart from T 0 and T S, the HRT is characterized also by the sinus cardiac length (SCL [ms]) computed as the average of the three RR-intervals previous the VPC, the compensatory pause (CP [ms]) which is the RR-interval just right after the VPC, and the coupling interval (CI [ms]) which isthe RR-interval corresponding to the VPC (see Table 1). HRV is usually assessed by time-domain and frequencydomain indices, which are computed on NN-interval time series from 24-hour Holter recordings.…”

Section: Sd1mentioning

confidence: 99%

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Quantifying the Autonomic Nervous System influence on Heart Rate Turbulence using Partial Least Squares Path Modeling

Puente-Díaz¹,

García-Carretero²,

Goya–Esteban³

et al. 2022

Computing in Cardiology Conference (CinC)

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Heart rate turbulence (HRT) is a physiological phenomenon used for cardiac risk stratification. Its alteration or absence indicates a significantly increased likelihood of mortality. However, the influence of the autonomic nervous system (ANS) on HRT needs to be further investigated. We propose a cause-effect relationship model to quantify the influence of the ANS. A set of 481 Holter-monitor recordings from different medical conditions were used, from THEW: acute myocardial infarction, coronary artery disease and end-stage renal disease. We proposed to model the relationship between HRT and ANS using Partial Least Squares Path Modeling (PLS-PM), a method for structural equation modeling that allows analyzing the relationships between the observed data and the latent variables. HRT parameters were estimated on individual ventricular premature complex (VPC) tachograms. ANS was assessed by heart rate variability indices computed from 3-min before VPC tachograms. The data set was split into low-risk and high-risk subgroups. SDN N , P LF , T S and T O were the most relevant variables. In low-risk, ANS activity was negatively related to HRT, while correlation between coupling interval and HRT on high-risk depends on the pathology. PLS-PM suggests that the influence of physiological variables on HRT is broken on high-risk. Results of the model are in agreement with the baroreflex hypothesis.1.

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Section: Sd1mentioning

confidence: 99%

“…The heart rate affects the strength of the HRT response, in a way that HRT is reduced at high heart rate. VPC prematurity also influences the HRT response [4,5]. As well, it has been studied in the literature some interaction effect between sex and age on HRT [6,7].…”

Section: Introductionmentioning

confidence: 99%

Quantifying the Autonomic Nervous System influence on Heart Rate Turbulence using Partial Least Squares Path Modeling

Puente-Díaz¹,

García-Carretero²,

Goya–Esteban³

et al. 2022

Computing in Cardiology Conference (CinC)

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Novel dual-reference approach facilitates the activation mapping and catheter ablation of premature atrial complexes with non-pulmonary vein and non-superior vena cava origins

Chen

Yang

et al. 2022

EP Europace

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Aims Activation mapping of premature atrial complexes (PACs) proves challenging due to interference by mechanical bumping and non-targeted ectopies. This study aims to compare the mapping efficacy, instant success, and long-term recurrence of catheter ablation for PACs with non-pulmonary vein (PV) and non-superior vena cava (SVC) origins between the novel dual-reference approach (DRA) and the routine single-reference approach (SRA) of mapping. Methods and results Patients with symptomatic, drug-refractory PACs, or frequent residual PACs after atrial tachyarrhythmia ablation were enrolled. During activation mapping, the coronary sinus (CS) catheter was used as the only timing reference in the SRA group. In the DRA group, another catheter, which was spatially separated from the CS catheter, was used as the second reference. The timing difference between the two references was used to discriminate the targeted PACs from the uninterested rhythms. Procedural parameters and long-term recurrence were compared. A total of 188 patients (109 in SRA and 79 in DRA) were enrolled. The baseline characteristics were similar. Compared with the SRA group, the DRA group had less repeated mapping (1.2 ± 0.4 vs. 1.4 ± 0.5, P = 0.004), shorter mapping (15 ± 6 vs. 23 ± 7 min, P < 0.001) and procedural time (119 ± 28 vs. 132 ± 22 min, P = 0.001), similar procedural complication rates (3.6 vs. 3.8%, P > 0.999), higher instant success (96.2 vs. 87.2%, P = 0.039), and lower recurrence rate (15.2 vs. 29.3%, hazard ratio 1.943, P = 0.033) during a 24-month follow-up. Conclusion As a novel strategy, the DRA shortens the procedural time and improves both instant and long-term success of PAC ablation, serving as a promising approach in mapping PACs with non-PV and non-SVC origins.

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Electrical myocardial instability as a problem of modern therapeutic practice – the realities of prognosis (a literature review)

Іванов

Shushkovska

Afanasiuk

et al. 2020

ZMJ

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On the Influence of Heart Rate and Coupling Interval Prematurity on Heart Rate Turbulence

Abstract: The results of this study can help to provide new risk indicators that take into account physiological influence on HRT, as well as to model how this influence changes in different cardiac conditions.

Cited by 5 publications

References 20 publications

Quantifying the Autonomic Nervous System influence on Heart Rate Turbulence using Partial Least Squares Path Modeling

Quantifying the Autonomic Nervous System influence on Heart Rate Turbulence using Partial Least Squares Path Modeling

Novel dual-reference approach facilitates the activation mapping and catheter ablation of premature atrial complexes with non-pulmonary vein and non-superior vena cava origins

Electrical myocardial instability as a problem of modern therapeutic practice – the realities of prognosis (a literature review)

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