The automatic detection of changes or anomalies between multispectral and hyperspectral images collected at different time instants is an active and challenging research topic. To effectively perform change-point detection in multitemporal images, it is important to devise techniques that are computationally efficient for processing large datasets, and that do not require knowledge about the nature of the changes. In this paper, we introduce a novel online framework for detecting changes in multitemporal remote sensing images. Acting on neighboring spectra as adjacent vertices in a graph, this algorithm focuses on anomalies concurrently activating groups of vertices corresponding to compact, well-connected and spectrally homogeneous image regions. It fully benefits from recent advances in graph signal processing to exploit the characteristics of the data that lie on irregular supports. Moreover, the graph is estimated directly from the images using superpixel decomposition algorithms. The learning algorithm is scalable in the sense that it is efficient and spatially distributed. Experiments illustrate the detection and localization performance of the method.