1971
DOI: 10.1016/s0022-5347(17)61567-2
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On the Etiology of Epididymitis

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Cited by 38 publications
(18 citation statements)
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“…Before tests for detecting Chlamydia trachomatis were available, the cause of most cases of acute epididymitis was unknown, and the condition was regarded as an enigma [4]; urethrovasal reflux was regarded as a likely aetiological factor [10]. Subsequent studies showed that epididymitis is mostly an infective condition (Table 1[11–19]).…”
Section: Microbiologymentioning
confidence: 99%
See 1 more Smart Citation
“…Before tests for detecting Chlamydia trachomatis were available, the cause of most cases of acute epididymitis was unknown, and the condition was regarded as an enigma [4]; urethrovasal reflux was regarded as a likely aetiological factor [10]. Subsequent studies showed that epididymitis is mostly an infective condition (Table 1[11–19]).…”
Section: Microbiologymentioning
confidence: 99%
“…The relationship between acute epididymitis and subfertility in men is poorly understood. Involvement of the testis by inflammation causes decreased spermatogenesis during acute epididymitis [10], and subsequent reduced spermatogenesis is a frequent consequence [85]. However, the incidence of long‐term subfertility after unilateral testicular involvement is unclear [86].…”
Section: Outcomes and Complicationsmentioning
confidence: 99%
“…Comparable observations have been made in a limited number of males (ethical limitations) suffering from acute epididymitis. In the acute phase, a reduction in spermatogenesis and an intratesticular invasion by polymorphonuclear cells were evident in such patients (Osegbe, ; Wolin, ), while in the follow‐up about 1 year later, disruption of testicular architecture associated with fibrosis, hyalinisation, hypospermatogenesis, maturation arrest or Sertoli cell‐only syndrome was reported (Dietz, ; Osegbe, ). This shows that genital tract infection is clearly related to impaired testicular architecture and also a possible disruption of the blood–testis barrier (Fijak et al, ; Lotti et al, ).…”
Section: Discussionmentioning
confidence: 99%
“…Acute epididymo-orchitis is a common clinical problem in urological practice, sometimes accounting for up to 24.5% of all urological admissions (Wolin, 1971). In 55 to 100% of cases there is no clear aetiology (Harnisch et al, 1977).…”
Section: Discussionmentioning
confidence: 99%