“…However, as discussed in more detail in our recent paper [5], nowadays no measurement method has been able to provide safe, economical, accurate and reliable estimates of pH in the bloodstream to be used routinely during ECC treatments, thus blood pH is generally not monitored during ECC treatments. To overcome all the above limitations, in our recent paper [5], we proposed and described a measuring system composed of a disposable fluorescent sensor and a non-disposable optical-head for the inline and real-time monitoring of blood-pH in extracorporealcirculation (ECC). In such a paper [5], we described the proposed measuring instrument and measurement method, we report about a preliminary investigation on biocompatibility and, finally, we reported the results obtained by simulating with bovine blood an about 6 h ECC treatment.…”