On the classification and nomenclature of baculoviruses: A proposal for revision

Jehle, Johannes A.; Blissard, Gary W.; Bonning, Bryony C.; Cory, Jenny S.; Herniou, Elisabeth A.; Rohrmann, George F.; Theilmann, David A.; Thiem, Suzanne M.; Vlak, Just M.

doi:10.1007/s00705-006-0763-6

Cited by 504 publications

(423 citation statements)

References 41 publications

Supporting

Mentioning

379

Contrasting

Unclassified

Order By: Relevance

“…A phylogenetic tree was inferred from a dataset of combined amino acid sequences of the 29 baculovirus core genes (Herniou et al, 2003;Jehle et al, 2006) of the 33 baculoviruses that had been completely sequenced at the time of analysis (Supplementary Table S1 available in JGV Online). Neighbourjoining (NJ) and maximum-parsimony (MP) analyses were performed using MEGA, version 3.1 (Kumar et al, 2004).…”

Section: Methodsmentioning

confidence: 99%

“…Based on the polyhedrin (polh) gene, NPVs are further subdivided into group I and group II (Bulach et al, 1999;Herniou et al, 2001Herniou et al, , 2003. Recent evidence shown from the comparison of 29 baculovirus genomes indicates that baculovirus phylogeny is aligned with the classification of the hosts more closely than with morphological traits (Afonso et al, 2001;Garcia-Maruniak et al, 2004;Lauzon et al, 2004;Jehle et al, 2006). An updated classification of the family Baculoviridae, which includes four generaAlphabaculovirus (lepidopteran-specific NPV), Betabaculovirus (lepidopteran-specific GV), Gammabaculovirus (hymenopteran-specific NPV) and Deltabaculovirus (dipteran-specific NPV) -was thus proposed (Lauzon et al, 2004;Jehle et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

“…Recent evidence shown from the comparison of 29 baculovirus genomes indicates that baculovirus phylogeny is aligned with the classification of the hosts more closely than with morphological traits (Afonso et al, 2001;Garcia-Maruniak et al, 2004;Lauzon et al, 2004;Jehle et al, 2006). An updated classification of the family Baculoviridae, which includes four generaAlphabaculovirus (lepidopteran-specific NPV), Betabaculovirus (lepidopteran-specific GV), Gammabaculovirus (hymenopteran-specific NPV) and Deltabaculovirus (dipteran-specific NPV) -was thus proposed (Lauzon et al, 2004;Jehle et al, 2006). Using whole genome sequence data to compare the genetic makeup of different baculoviruses may help to determine which genes are essential for these viruses and help in understanding host range, virulence and morphology.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Genomic and host range studies of Maruca vitrata nucleopolyhedrovirus

Chen

Lee

et al. 2008

Journal of General Virology

View full text Add to dashboard Cite

The complete genome of the Maruca vitrata nucleopolyhedrovirus (MaviNPV) isolated from the legume pod borer, Maruca vitrata (Lepidoptera: Pyralidae), was sequenced. It was found to be 111 953 bp in length, with an overall 39 % G+C content, and contained 126 open reading frames (ORFs) encoding predicted proteins of over 50 aa. The gene content and gene order of MaviNPV have the highest similarity to those of Autographa californica multiple nucleopolyhedrovirus (AcMNPV) and their shared homologous genes are 100 % collinear. In fact, MaviNPV seems to be a mini-AcMNPV that is native to Taiwan and possesses a smaller genome with fewer auxiliary genes than the AcMNPV type species. Except for one ORF (Mv74), all of the MaviNPV ORFs have homologues in the AcMNPV genome. MaviNPV is the first lepidopteranspecific baculovirus to lack homologues of vfgf and odv-e66. In addition, MaviNPV lacks the baculovirus repeat ORF (bro) gene that corresponds to AcMNPV ORF2. Five homologous regions (hrs) were located within the MaviNPV genome, and these contained a total of 44 imperfect palindromes. Phylogenetic analysis of the whole genome revealed that MaviNPV was separated from the common ancestor of AcMNPV and Bombyx mori nucleopolyhedrovirus before these two viral species diverged from each other. Moreover, replication of MaviNPV in several cell lines and an egfp-MaviNPV infection assay revealed that IPLB-LD-652Y cells are only partially permissive to MaviNPV, which supports our conclusion that MaviNPV is a distinct species of the group I lepidopteran NPVs.

show abstract

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Genomic and host range studies of Maruca vitrata nucleopolyhedrovirus

Chen

Lee

et al. 2008

Journal of General Virology

View full text Add to dashboard Cite

show abstract

“…AcMNPV are enveloped viruses having circular double stranded DNA (134 kbp) contained in 15-40 9 200-300 nm size rod shaped nucleocapsids [8]. They belong to genus Alpha baculovirus of Baculoviridae, that specifically infect insects in the order Lepidoptera [10]. The AcMNPV can however transduce mammalian cells, though its replication is restricted to insect cells [3].…”

Section: Introductionmentioning

confidence: 99%

Baculovirus mediated transduction: analysis of vesicular stomatitis virus glycoprotein pseudotyping

et al. 2014

View full text Add to dashboard Cite

The recombinant baculoviruses were constructed to investigate the necessity of VSV-G pseudotyping for mammalian cell transduction. The viruses were designed to express green fluorescent protein (GFP) gene under the control of cytomegalovirus promoter, with or without pseudotyping with VSV-G. VSV-G was placed under the control of polyhedrin promoter that is recognized by insect cells, allowing the formation of pseudotyped baculovirus. The study findings demonstrate that the pseudotyping of baculovirus significantly enhanced transduction efficiency compared to non-pseudotyped baculovirus, resulting in consequent distinction in the expression of GFP in mammalian cells. The results confirmed that pseudotyping is important for baculovirus mediated gene delivery. Further, when full-length VSV-G pseudotyping was compared with truncated VSV-G containing GED domain (G-stem of ectodomain in conjunction with the TM and CT domains of the glycoprotein), latter was relatively less efficient in transducing mammalian cells. This study demonstrated that pseudotyping with full-length VSV-G had better transduction efficiency in mammalian cells. However, at higher multiplicity of infection, both fulllength and truncated VSV-G showed equivalent transduction. This study established the significance of pseudotyping of baculovirus with full-length VSV-G for efficient transduction of mammalian cells, utilizing the highly sensitive GFP marker system. These findings have significant implications in designing of baculovirus vector based antigen delivery for developing new generation vaccines.

show abstract

“…Baculoviruses are members of a single family, the Baculoviridae, which is divided into four genera, Alpha-, Gamma-and Deltabaculovirus (formally known collectively as the genus Nucleopolyhedroivrus (NPV)) and Betabaculovirus formerly known as the genus Granulovirus (GV), based on molecular phylogeny and host insects (Jehle et al, 2006). Nucleopolyhedroviruses also can be divided into two groups, group I and II, by phylogenetic analysis of several genes including polyhedrin (Zanotto et al, 1993;Herniou et al, 2001).…”

Section: Introductionmentioning

confidence: 99%

Hyphantria cunea Nucleopolyhedrovirus, a Novel Baculovirus Isolated from Fall Webworm in Korea

Heo¹,

Choi²,

Bae³

et al. 2011

International Journal of Industrial Entomology

View full text Add to dashboard Cite

To elucidate the novelty of Hyphantria cunea nucleopolyhedrovirus (HcNPV) isolated in Korea, polyhedrin and inhibitor of apoptosis (iap) gene structures were determined and analyzed. The analysis of HcNPV polyhedrin showed a little difference with 97.6% at the nucleotide level but no difference at the amino acid level when compared with that of previously reported H. cunea NPV (HycuNPV). On the other hand, iap genes showed variable differences with 89.0-99.6% nucleotide and 90.0-99.6% amino acid sequence identities. Especially, the 5' and 3' non-coding flanking sequences of iap1 gene had lower degree of identity with those of HycuNPV. Although the phylogenetic analyses using polyhedrin and iap genes showed that HcNPV is closely related with HycuNPV, we could provide that HcNPV is a novel isolate having novel gene structures.

show abstract

On the classification and nomenclature of baculoviruses: A proposal for revision

Cited by 504 publications

References 41 publications

Genomic and host range studies of Maruca vitrata nucleopolyhedrovirus

Genomic and host range studies of Maruca vitrata nucleopolyhedrovirus

Baculovirus mediated transduction: analysis of vesicular stomatitis virus glycoprotein pseudotyping

Hyphantria cunea Nucleopolyhedrovirus, a Novel Baculovirus Isolated from Fall Webworm in Korea

Contact Info

Product

Resources

About