In this paper the authors provide a complete answer to Donkin's Tilting Module Conjecture for all rank 2 semisimple algebraic groups and SL4(k) where k is an algebraically closed field of characteristic p > 0. In the process, new techniques are introduced involving the existence of (p, r)-filtrations, Lusztig's character formula, and the GrT-radical series for baby Verma modules.