On-spot surface enhanced Raman scattering detection of Aflatoxin B1 in peanut extracts using gold nanobipyramids evenly trapped into the AAO nanoholes

Lin, Bingyong; Kannan, Palanisamy; Qiu, Bin; Lin, Zhenyu; Guo, Longhua

doi:10.1016/j.foodchem.2019.125528

Cited by 54 publications

(36 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The sandwich structure enhances the Raman signal from Raman reporter molecules on the surface of Au nanocages and Au nanostars, [171] c) Fabrication of planar SERS substrate by the deposition of Au bipyramid (AuBPs) inside the nanoholes of anodic aluminium oxide for detection of detect the aflatoxin B1. [153] [187] and formation of hot-spots between them (Figure 10c). The asdeveloped SERS substrate was then used to detect the aflatoxin B1 in the peanut extract with a LOD of 0.5 μg/L.…”

Section: Planar Sers Biosensorsmentioning

confidence: 99%

“…Recently, planar SERS sensors using other substrates such as silicon (Si) wafer have been reported. Lin et al [153] have used the anodic aluminium oxide (AAO) as a template to form the Au bipyramids (AuBPs) hotspots. They dropped the solution of AuBPs into the nanoholes of AAO and dried the solvent by a paper, causing the aggregation of AuBPs into the nanoholes Figure 10.…”

Section: Planar Sers Biosensorsmentioning

confidence: 99%

See 1 more Smart Citation

Metal Nanoparticles‐Enhanced Biosensors: Synthesis, Design and Applications in Fluorescence Enhancement and Surface‐enhanced Raman Scattering

Yaraki

Tan

2020

Chemistry An Asian Journal

View full text Add to dashboard Cite

Metal nanoparticles (NP) that exhibit localized surface plasmon resonance play an important role in metalenhanced fluorescence (MEF) and surface-enhanced Raman scattering (SERS). Among the optical biosensors, MEF and SERS stand out to be the most sensitive techniques to detect a wide range of analytes from ions, biomolecules to macromolecules and microorganisms. Particularly, anisotropic metal NPs with strongly enhanced electric field at their sharp corners/edges under a wide range of excitation wavelengths are highly suitable for developing the ultrasensitive plasmonenhanced biosensors. In this review, we first highlight the reliable methods for the synthesis of anisotropic gold NPs and silver NPs in high yield, as well as their alloys and composites with good control of size and shape. It is followed by the discussion of different sensing mechanisms and recent advances in the MEF and SERS biosensor designs. This includes the review of surface functionalization, bioconjugation and (directed/self) assembly methods as well as the selection/screening of specific biorecognition elements such as aptamers or antibodies for the highly selective biodetection. The right combinations of metal nanoparticles, biorecognition element and assay design will lead to the successful development of MEF and SERS biosensors targeting different analytes both in-vitro and in-vivo. Finally, the prospects and challenges of metal-enhanced biosensors for future nanomedicine in achieving ultrasensitive and fast medical diagnostics, high-throughput drug discovery as well as effective and reliable theranostic treatment are discussed.

show abstract

Section: Planar Sers Biosensorsmentioning

confidence: 99%

Section: Planar Sers Biosensorsmentioning

confidence: 99%

Metal Nanoparticles‐Enhanced Biosensors: Synthesis, Design and Applications in Fluorescence Enhancement and Surface‐enhanced Raman Scattering

Yaraki

Tan

2020

Chemistry An Asian Journal

View full text Add to dashboard Cite

show abstract

“…It attributes the enhancement to the enhanced local electric field near the metal surface, which is not related to the adsorbed species. The EM effect is paramount when investigating substrates of SERS, such as the “hot spot” effect of the nanoscale rough surface of noble metals [ 34 , 35 , 36 , 37 , 38 ]. With the aid of the CE effect and EM effect, SERS can enhance the weak inelastic Raman scattering signal tremendously.…”

Section: Introductionmentioning

confidence: 99%

Fast and Low-Cost Surface-Enhanced Raman Scattering (SERS) Method for On-Site Detection of Flumetsulam in Wheat

2020

View full text Add to dashboard Cite

The pesticide residues in agri-foods are threatening people’s health. This study aims to establish a fast and low-cost surface-enhanced Raman scattering (SERS) method for the on-site detection of flumetsulam in wheat. The two-step modified concentrated gold nanoparticles (AuNPs) acted as the SERS substrate with the aid of NaCl and MgSO4. NaCl is served as the activator to modify AuNPs, while MgSO4 is served as the aggregating agent to form high-density hot spots. The activation and aggregation are two essential collaborative procedures to generate remarkable SERS enhancement and achieve the trace-level detection of flumetsulam. This method exhibits good enhancement effect with an enhancement factor of 106 and wide linear range (5–1000 μg/L). With simple pretreatment, the flumetsulam residue in real wheat samples can be successfully detected with the limit of detection (LOD) down to 0.01 μg/g, which is below the maximum residue limit of flumetsulam in wheat (0.05 μg/g) set in China. The recovery of flumetsulam residue in wheat ranges from 88.3% to 95.6%. These results demonstrate that the proposed SERS method is a powerful technique for the detection of flumetsulam in wheat, which implies the great application potential in the rapid detection of other pesticide residues in various agri-foods.

show abstract

“…Anodic aluminum oxide (AAO) has been used as a mask to fabricate nanodot SERS substrates [ 40 – 43 ]. Using an AAO mask, Han et al [ 41 ] manufactured graphene/Au nanodot array structures, which were used as SERS substrates.…”

Section: Introductionmentioning

confidence: 99%

“…Using an AAO template, Aflatoxin B 1 (AFB 1 ) from peanut extract was detected at concentrations ranging from 1.5 µg/L to 1.5 mg/L. Although the method is suitable for the evaluation of AFB 1 content in food safety inspections [ 43 ], the fabrication process for generating the AAO is lengthy.…”

Section: Introductionmentioning

confidence: 99%

Fabrication of nano/microstructures for SERS substrates using an electrochemical method

Zhang

Jia

et al. 2020

Beilstein J. Nanotechnol.

View full text Add to dashboard Cite

Based on an electrochemical method, three-dimensional arrayed nanopore structures are machined onto a Mg surface. The structured Mg surface is coated with a thin gold (Au) film, which is used as a surface-enhanced Raman scattering (SERS) substrate. A rhodamine 6G (R6G) probe molecule is used as the detection agent for the SERS measurement. Different sizes of arrayed micro/nanostructures are fabricated by different treatment time using the electrochemical process. The topographies of these micro/nanostructures and the thickness of the Au film have an influence on the Raman intensity of the Mg substrate. Furthermore, when the thickness of Au film coating is held constant, the Raman intensity on the structured Mg substrates is about five times higher after a treatment time of 1 min when compared with other treatment times. The SERS enhancement factor ranges from 106 to 1.75 × 107 under these experimental conditions. Additionally, a 10−6 mol·L−1 solution of lysozyme was successfully detected using the Mg–Au nanopore substrates. Our low-cost method is reproducible, homogeneous, and suitable for the fabrication of SERS substrates.

show abstract

On-spot surface enhanced Raman scattering detection of Aflatoxin B1 in peanut extracts using gold nanobipyramids evenly trapped into the AAO nanoholes

Cited by 54 publications

References 38 publications

Metal Nanoparticles‐Enhanced Biosensors: Synthesis, Design and Applications in Fluorescence Enhancement and Surface‐enhanced Raman Scattering

Metal Nanoparticles‐Enhanced Biosensors: Synthesis, Design and Applications in Fluorescence Enhancement and Surface‐enhanced Raman Scattering

Fast and Low-Cost Surface-Enhanced Raman Scattering (SERS) Method for On-Site Detection of Flumetsulam in Wheat

Fabrication of nano/microstructures for SERS substrates using an electrochemical method

Contact Info

Product

Resources

About