On-site Cytopathologic Analysis of Bronchoscopic Needle Aspiration

Boyan, William

doi:10.1097/00128594-200304000-00016

Cited by 11 publications

(5 citation statements)

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“…Several studies have reported the utility of ROSE during TBNA [8,[23][24][25][26][27]. The technique has been described as effective and capable of increasing the diagnostic yield [24,25] and reduce the number of aspirates [23,26], the need for additional diagnostic procedures [8,23,26], the complication rate of bronchoscopy [23], and the cost [8].…”

Section: Discussionmentioning

confidence: 99%

“…The technique has been described as effective and capable of increasing the diagnostic yield [24,25] and reduce the number of aspirates [23,26], the need for additional diagnostic procedures [8,23,26], the complication rate of bronchoscopy [23], and the cost [8]. Although it remains controversial [27], many specialists now recommend the use of ROSE during TBNA [28] although the benefit of ROSE during EBUS-TBNA may be smaller than that during TBNA because EBUS-TBNA provides a high diagnostic yield even without ROSE. So far, only a few studies [14,29,30] have investigated the utility of ROSE during EBUS-TBNA.…”

Section: Discussionmentioning

confidence: 99%

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Endobronchial ultrasound-guided transbronchial needle aspiration in the diagnosis of small cell lung cancer

Murakami

Oki

Sasaki

et al. 2014

Respiratory Investigation

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Endobronchial ultrasound-guided transbronchial needle aspiration in the diagnosis of small cell lung cancer

Murakami

Oki

Sasaki

et al. 2014

Respiratory Investigation

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“…Expert panels have stated that the use of on‐site cytological evaluation during EBUS‐TBNA reduces the need for additional procedures 5 . However, its utility for LN staging in lung cancer for certain investigators is still controversial, 4‐7 and not widely used in some institutions 8,9 . Notably, most of the previous studies against the use of c‐ROSE show no evidence that cytological on‐site evaluation was performed by an experienced cytopathology team or describe the details of cytology assistance 5 …”

Section: Discussionmentioning

confidence: 99%

Optimising rapid on‐site evaluation‐assisted endobronchial ultrasound‐guided transbronchial needle aspiration of mediastinal lymph nodes: The real‐time cytopathology intervention process

et al. 2021

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Introduction Lymph node sampling by endobronchial ultrasound‐guided transbronchial needle aspiration (EBUS‐TBNA) is the state of art procedure for staging the mediastinum and hilar regions in lung cancer patients. Our experience of implementing the real‐time cytopathology intervention (RTCI) process for intraoperative EBUS‐TBNAs is presented. This study is aimed to describe in detail the RTCI process for EBUS‐TBNAs, and assess its utility and diagnostic yield before and after its implementation in parallel to conventional rapid on‐site evaluation (c‐ROSE). Methods A retrospective review of all EBUS‐TBNAs between July 2016 and July 2017 at the University of Rochester Medical Center was performed. Final diagnoses, patient clinical data, and number of non‐diagnostic samples (NDS) were reviewed. The numbers of NDS obtained from EBUS‐TBNAs with no cytology assistance (NCA), with RTCI and with c‐ROSE were analysed. Results Non‐diagnostic lymph node samples were found in 20 out of 116 (17%), three out of 114 (2.6%) and 33 out of 286 (11.5%) cases with NCA, RTCI and c‐ROSE, respectively. Application of statistical analysis revealed significant difference in the NDS between the groups of cases in the operating room with NCA and RTCI (P = .005). The different settings and variables between the cases performed using RTCI in the operating room and those assisted with c‐ROSE in the bronchoscopy suite preclude legitimate comparison. Conclusion Our results indicate that the use of RTCI could yield a significantly low proportion of NDS when assisting EBUS‐TBNA of mediastinal and hilar lymph node for lung cancer patients enhancing the diagnostic efficiency of the procedure.

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“…The usefulness of ROSE was undoubted since 2005, when Baram et al published another observational trial which, for the first time, failed to show an increase of the diagnostic yield or the specimen's adequacy for the patients undergoing ROSE, yet suggested that onsite review allowed to avoid additional sampling without loss in diagnostic yield [4]. The results of this study prompted a critical re-evaluation of the clinical research regarding ROSE, which led to the identification of several problems limiting the reliability of the results from the above studies [5,6].…”

mentioning

confidence: 84%