On Primary Adrenal Insufficiency with Normal Concentrations of
Cortisol – Early Manifestation of Addison’s
Disease
Hanna Wäscher,
Andreas Knauerhase,
Bettina Klar
et al.
Abstract:Primary adrenal insufficiency (AI) is an endocrine disorder in which hormones of
the adrenal cortex are produced to an insufficient extent. Since receptors for
adrenal steroids have a wide distribution, initial symptoms may be nonspecific.
In particular, the lack of glucocorticoids can quickly lead to a
life-threatening adrenal crisis. Therefore, current guidelines suggest applying
a low threshold for testing an… Show more
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