Abstract. This paper presents a complete custom full-digital instrumentation device that was designed for real-time neutron flux estimation, especially for nuclear reactor incore measurement using subminiature Fission Chambers (FCs). Entire fully functional small-footprint design (about 1714 LUTs) is implemented on FPGA. It enables real-time acquisition and analysis of multiple channels neutron's flux both in counting mode and Campbelling mode. Experimental results obtained from this brand new device are consistent with simulation results and show good agreement within good uncertainty. This device paves the way for new applications perspectives in real-time nuclear reactor monitoring.