1999
DOI: 10.1016/s0168-1656(99)00008-5
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On-line monitoring of fungal cell concentration by dielectric spectroscopy

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Cited by 17 publications
(7 citation statements)
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“…The largest utilization of oxygen during the growth of aerobic microorganisms is for respiration. Oxygen acts as a terminal electron acceptor for oxidative reactions to provide energy for cellular activities [112]. Productivity of several fermentations is limited by oxygen availability and it is therefore important to consider the factors, which affect the efficiency in supplying microbial cells with oxygen [113].…”
Section: Effect Of Agitation and Aerationmentioning
confidence: 99%
“…The largest utilization of oxygen during the growth of aerobic microorganisms is for respiration. Oxygen acts as a terminal electron acceptor for oxidative reactions to provide energy for cellular activities [112]. Productivity of several fermentations is limited by oxygen availability and it is therefore important to consider the factors, which affect the efficiency in supplying microbial cells with oxygen [113].…”
Section: Effect Of Agitation and Aerationmentioning
confidence: 99%
“…Dielectric spectroscopy was first proposed for on-line biomass monitoring by Harris et al (1987), and has since found acceptance in many laboratory and industrial facilities worldwide. It has been used to monitor animal cell culture (Davey et al, 1988;Degouys et al, 1993;Ducommun et al, 2001a, Guan et al, 1998Noll and Biselli, 1998;Siano, 1997;Zeiser et al, 1999), plant cell culture (Markx et al, 1991) and microbial fermentation Gheorghiu and Asami, 1998;Krairak et al, 1999;Markx and Kell, 1995;Nicholson et al, 1996;November and van Impe, 2000;Penaloza et al, 1992;Siano, 1997).…”
Section: Introductionmentioning
confidence: 99%
“…The overriding goal is to lower quality control costs without lowering effectiveness. Utilization of PAT for real-time batch release reduces the cost Hill and Thommel (1982); Thompson et al (1985); Kole et al (1985) Deutsche Hefewerke Akhnoukh et al (1996); Armiger et al (1984); Li and Humphrey (1991); Scheper et al (1987); Schügerl (2001) Radio frequency impedance Carvell (2003) Dielectric constant (permittivity) Krairak et al (1999) Optical density (turbidity) Junker et al (1994);van Putten et al (1996); Wipf et al (1994); Yamane et al (1992); Zhou and Hu (1994) Hoffmann-LaRoche, Merck…”
Section: Real-time Batch Releasementioning
confidence: 99%