On-line coupling of gradient-HPLC and1H NMR for the analysis of random poly[(styrene)-co-(ethyl acrylate)]s

On-line coupling of high temperature GPC and 1H NMR for the analysis of polymers

“…Further studies on coupled HPLC-NMR have shown the power of liquid adsorption chromatography (LAC) for the analysis of polymers regarding the chemical composition [8][9][10][11][12][13]. It was shown that polyethylene oxides can be analysed with regard to functionality type distribution by identifying the different end groups [8].…”

“…The critical point of adsorption was also used for the analysis of tacticity of poly(ethyl methacrylate)s by HPLC-NMR [12]. In further studies on copolymers, gradient HPLC-NMR was used for the analysis of the CCD of random poly(styrene-co-ethyl acrylate) copolymers [13]. The same copolymer system was also studied by GPC-NMR [14].…”

Multidimensional HPLC of Polymers

“…Krämer et al reported about SEC-NMR for the chemical composition analysis of poly(styrene-cobutyl acrylate) copolymers [152]. Further studies on coupled HPLC-NMR have shown the power of liquid adsorption chromatography (LAC) for the analysis of polymers regarding the chemical composition [153][154][155][156][157][158]. It was shown that polyethylene oxides can be analyzed with regard to functionality type distribution by identifying the different endgroups [153].…”

“…sufficiently high flow rate, moderate sample concentration, and on-flow detection. In further studies on copolymers, gradient HPLC-NMR was used for the analysis of the CCD of random poly(styrene-co-ethyl acrylate) copolymers [158]. It has been shown that LCCC coupled to NMR allows for the full assignment of the chemical structure and the degree of polymerization of all 220 7 Hyphenation of Polymer Chromatography with Information-Rich Detectors oligomer species in complex mixtures [155,156].…”

Structure Determination of Polyacetals by Liquid Chromatography and Hyphenated Techniques

“…As a result of this two-dimensional (2D) separation, information on both types of heterogeneity is obtained. Another useful approach is the combination of a selective chromatographic technique with a powerful spectroscopic method like NMR spectroscopy [1][2][3][4][5] or matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). [6,7] There are numerous selective modes for the liquid chromatography (LC) of polymers, including liquid chromatography at the critical point of adsorption (LCCC) [8][9][10] and isocratic or gradient polymer elution chromatography (GPEC).…”